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Tumor and blood B-cell abundance outperforms established immune checkpoint blockade response prediction signatures in head and neck cancer.
Chang TG, Spathis A, Schäffer AA, Gavrielatou N, Kuo F, Jia D, Mukherjee S, Sievers C, Economopoulou P, Anastasiou M, Moutafi M, Pal LR, Vos J, Lee AS, Lam S, Zhao K, Jiang P, Allen CT, Foukas P, Gomatou G, Altan-Bonnet G, Morris LGT, Psyrri A, Ruppin E. Chang TG, et al. Among authors: ruppin e. Ann Oncol. 2024 Nov 17:S0923-7534(24)04914-7. doi: 10.1016/j.annonc.2024.11.008. Online ahead of print. Ann Oncol. 2024. PMID: 39551185
Decoupling the correlation between cytotoxic and exhausted T lymphocyte transcriptomic signatures enhances melanoma immunotherapy response prediction from tumor expression.
Wang B, Wang K, Jiang P, Ruppin E. Wang B, et al. Among authors: ruppin e. bioRxiv [Preprint]. 2023 Jul 3:2023.01.17.524482. doi: 10.1101/2023.01.17.524482. bioRxiv. 2023. Update in: iScience. 2024 May 07;27(6):109926. doi: 10.1016/j.isci.2024.109926 PMID: 36789444 Free PMC article. Updated. Preprint.
Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion.
Cohen Shvefel S, Pai JA, Cao Y, Pal LR, Levy R, Yao W, Cheng K, Zemanek M, Bartok O, Weller C, Yin Y, Du PP, Yakubovich E, Orr I, Ben-Dor S, Oren R, Fellus-Alyagor L, Golani O, Goliand I, Ranmar D, Savchenko I, Ketrarou N, Schäffer AA, Ruppin E, Satpathy AT, Samuels Y. Cohen Shvefel S, et al. Among authors: ruppin e. bioRxiv [Preprint]. 2023 Nov 29:2023.11.29.569032. doi: 10.1101/2023.11.29.569032. bioRxiv. 2023. PMID: 38077050 Free PMC article. Preprint.
Deactivation of ligand-receptor interactions enhancing lymphocyte infiltration drives melanoma resistance to Immune Checkpoint Blockade.
Sahni S, Wang B, Wu D, Dhruba SR, Nagy M, Patkar S, Ferreira I, Wang K, Ruppin E. Sahni S, et al. Among authors: ruppin e. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558683. doi: 10.1101/2023.09.20.558683. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 14;15(1):8867. doi: 10.1038/s41467-024-52555-4 PMID: 37886558 Free PMC article. Updated. Preprint.
Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Long-Term Risk of Immune-Related diseases.
Israel A, Schäffer AA, Berkovitch M, Ozeri DJ, Merzon E, Green I, Golan-Cohen A, Ruppin E, Vinker S, Magen E. Israel A, et al. Among authors: ruppin e. medRxiv [Preprint]. 2023 Mar 24:2023.03.23.23287616. doi: 10.1101/2023.03.23.23287616. medRxiv. 2023. Update in: Front Immunol. 2023 Sep 11;14:1232560. doi: 10.3389/fimmu.2023.1232560 PMID: 37090544 Free PMC article. Updated. Preprint.
The expression patterns of different cell types and their interactions in the tumor microenvironment are predictive of breast cancer patient response to neoadjuvant chemotherapy.
Dhruba SR, Sahni S, Wang B, Wu D, Rajagopal PS, Schmidt Y, Shulman ED, Sinha S, Sammut SJ, Caldas C, Wang K, Ruppin E. Dhruba SR, et al. Among authors: ruppin e. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.598770. doi: 10.1101/2024.06.14.598770. bioRxiv. 2024. PMID: 39372749 Free PMC article. Preprint.
356 results