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Tumor and blood B-cell abundance outperforms established immune checkpoint blockade response prediction signatures in head and neck cancer.
Chang TG, Spathis A, Schäffer AA, Gavrielatou N, Kuo F, Jia D, Mukherjee S, Sievers C, Economopoulou P, Anastasiou M, Moutafi M, Pal LR, Vos J, Lee AS, Lam S, Zhao K, Jiang P, Allen CT, Foukas P, Gomatou G, Altan-Bonnet G, Morris LGT, Psyrri A, Ruppin E. Chang TG, et al. Among authors: jiang p. Ann Oncol. 2024 Nov 17:S0923-7534(24)04914-7. doi: 10.1016/j.annonc.2024.11.008. Online ahead of print. Ann Oncol. 2024. PMID: 39551185
Decoupling the correlation between cytotoxic and exhausted T lymphocyte transcriptomic signatures enhances melanoma immunotherapy response prediction from tumor expression.
Wang B, Wang K, Jiang P, Ruppin E. Wang B, et al. Among authors: jiang p. bioRxiv [Preprint]. 2023 Jul 3:2023.01.17.524482. doi: 10.1101/2023.01.17.524482. bioRxiv. 2023. Update in: iScience. 2024 May 07;27(6):109926. doi: 10.1016/j.isci.2024.109926 PMID: 36789444 Free PMC article. Updated. Preprint.
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors.
Sinha S, Vegesna R, Mukherjee S, Kammula AV, Dhruba SR, Wu W, Kerr DL, Nair NU, Jones MG, Yosef N, Stroganov OV, Grishagin I, Aldape KD, Blakely CM, Jiang P, Thomas CJ, Benes CH, Bivona TG, Schäffer AA, Ruppin E. Sinha S, et al. Among authors: jiang p. Nat Cancer. 2024 Jun;5(6):938-952. doi: 10.1038/s43018-024-00756-7. Epub 2024 Apr 18. Nat Cancer. 2024. PMID: 38637658
Big data in basic and translational cancer research.
Jiang P, Sinha S, Aldape K, Hannenhalli S, Sahinalp C, Ruppin E. Jiang P, et al. Nat Rev Cancer. 2022 Nov;22(11):625-639. doi: 10.1038/s41568-022-00502-0. Epub 2022 Sep 5. Nat Rev Cancer. 2022. PMID: 36064595 Free PMC article. Review.
Prediction of cancer treatment response from histopathology images through imputed transcriptomics.
Hoang DT, Dinstag G, Hermida LC, Ben-Zvi DS, Elis E, Caley K, Sammut SJ, Sinha S, Sinha N, Dampier CH, Stossel C, Patil T, Rajan A, Lassoued W, Strauss J, Bailey S, Allen C, Redman J, Beker T, Jiang P, Golan T, Wilkinson S, Sowalsky AG, Pine SR, Caldas C, Gulley JL, Aldape K, Aharonov R, Stone EA, Ruppin E. Hoang DT, et al. Among authors: jiang p. Res Sq [Preprint]. 2023 Sep 15:rs.3.rs-3193270. doi: 10.21203/rs.3.rs-3193270/v1. Res Sq. 2023. Update in: Nat Cancer. 2024 Sep;5(9):1305-1317. doi: 10.1038/s43018-024-00793-2 PMID: 37790315 Free PMC article. Updated. Preprint.
A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics.
Hoang DT, Dinstag G, Shulman ED, Hermida LC, Ben-Zvi DS, Elis E, Caley K, Sammut SJ, Sinha S, Sinha N, Dampier CH, Stossel C, Patil T, Rajan A, Lassoued W, Strauss J, Bailey S, Allen C, Redman J, Beker T, Jiang P, Golan T, Wilkinson S, Sowalsky AG, Pine SR, Caldas C, Gulley JL, Aldape K, Aharonov R, Stone EA, Ruppin E. Hoang DT, et al. Among authors: jiang p. Nat Cancer. 2024 Sep;5(9):1305-1317. doi: 10.1038/s43018-024-00793-2. Epub 2024 Jul 3. Nat Cancer. 2024. PMID: 38961276
Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages.
Valencia JC, Erwin-Cohen RA, Clavijo PE, Allen C, Sanford ME, Day CP, Hess MM, Johnson M, Yin J, Fenimore JM, Bettencourt IA, Tsuneyama K, Romero ME, Klarmann KD, Jiang P, Bae HR, McVicar DW, Merlino G, Edmondson EF, Anandasabapathy N, Young HA. Valencia JC, et al. Among authors: jiang p. Cancer Res. 2021 Dec 1;81(23):5977-5990. doi: 10.1158/0008-5472.CAN-21-1148. Epub 2021 Oct 12. Cancer Res. 2021. PMID: 34642183 Free PMC article.
5,658 results