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Sulfonamide-Pyrazole derivatives as next-generation Cyclooxygenase-2 enzyme inhibitors: From molecular design to in vivo efficacy.
Elgohary MK, Elkotamy MS, Alkabbani MA, El Hassab MA, Al-Rashood ST, Binjubair FA, Alsulaimany M, Ghabbour HA, Eldehna WM, Abdel-Aziz HA. Elgohary MK, et al. Among authors: elkotamy ms. Int J Biol Macromol. 2024 Dec 28:139170. doi: 10.1016/j.ijbiomac.2024.139170. Online ahead of print. Int J Biol Macromol. 2024. PMID: 39736293
Molecular docking, DFT and antiproliferative properties of 4-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition potency.
Binjubair FA, Almansour BS, Ziedan NI, Abdel-Aziz AA, Al-Rashood ST, Elgohary MK, Elkotamy MS, Abdel-Aziz HA. Binjubair FA, et al. Among authors: elkotamy ms. Drug Dev Res. 2024 Nov;85(7):e70009. doi: 10.1002/ddr.70009. Drug Dev Res. 2024. PMID: 39467111