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Bruton's tyrosine kinase (BTK) and matrix metalloproteinase-9 (MMP-9) regulate NLRP3 inflammasome-dependent cytokine and neutrophil extracellular trap responses in primary neutrophils.
Leal VNC, Bork F, Mateo Tortola M, von Guilleaume JC, Greve CL, Bugl S, Danker B, Bittner ZA, Grimbacher B, Pontillo A, Weber ANR. Leal VNC, et al. Among authors: bork f. J Allergy Clin Immunol. 2024 Nov 14:S0091-6749(24)01186-2. doi: 10.1016/j.jaci.2024.10.035. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39547282 Free article.
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation.
Bork F, Greve CL, Youn C, Chen S, N C Leal V, Wang Y, Fischer B, Nasri M, Focken J, Scheurer J, Engels P, Dubbelaar M, Hipp K, Zalat B, Szolek A, Wu MJ, Schittek B, Bugl S, Kufer TA, Löffler MW, Chamaillard M, Skokowa J, Kramer D, Archer NK, Weber ANR. Bork F, et al. EMBO Rep. 2024 Jul;25(7):2914-2949. doi: 10.1038/s44319-024-00150-5. Epub 2024 May 23. EMBO Rep. 2024. PMID: 38783164 Free PMC article.
Modified "Jurdham" procedure after left ventricular lead failure.
Zezyk C, Bork F, Boehmer AA, Ehrlich JR. Zezyk C, et al. Among authors: bork f. Herzschrittmacherther Elektrophysiol. 2022 Dec;33(4):458-459. doi: 10.1007/s00399-022-00891-7. Epub 2022 Sep 5. Herzschrittmacherther Elektrophysiol. 2022. PMID: 36063210 English. No abstract available.
Automation isn't automatic.
Christensen M, Yunker LPE, Shiri P, Zepel T, Prieto PL, Grunert S, Bork F, Hein JE. Christensen M, et al. Among authors: bork f. Chem Sci. 2021 Oct 27;12(47):15473-15490. doi: 10.1039/d1sc04588a. eCollection 2021 Dec 8. Chem Sci. 2021. PMID: 35003576 Free PMC article. Review.
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Bittner ZA, Liu X, Mateo Tortola M, Tapia-Abellán A, Shankar S, Andreeva L, Mangan M, Spalinger M, Kalbacher H, Düwell P, Lovotti M, Bosch K, Dickhöfer S, Marcu A, Stevanović S, Herster F, Cardona Gloria Y, Chang TH, Bork F, Greve CL, Löffler MW, Wolz OO, Schilling NA, Kümmerle-Deschner JB, Wagner S, Delor A, Grimbacher B, Hantschel O, Scharl M, Wu H, Latz E, Weber ANR. Bittner ZA, et al. Among authors: bork f. J Exp Med. 2021 Nov 1;218(11):e20201656. doi: 10.1084/jem.20201656. Epub 2021 Sep 23. J Exp Med. 2021. PMID: 34554188 Free PMC article.
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