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Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
Ding X, Liang J, Sharko AC, Hilimire TA, Li J, Loskutov J, Mack ZT, Ji H, Schools GP, Cai C, Pugacheva EN, Chen M, Roninson IB, Broude EV. Ding X, et al. Among authors: pugacheva en. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2414501121. doi: 10.1073/pnas.2414501121. Epub 2024 Nov 14. Proc Natl Acad Sci U S A. 2024. PMID: 39541354 Free PMC article.
Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors.
Whately KM, Voronkova MA, Maskey A, Gandhi J, Loskutov J, Choi H, Yanardag S, Chen D, Wen S, Margaryan NV, Smolkin MB, Purazo ML, Hu G, Pugacheva EN. Whately KM, et al. Among authors: pugacheva en. Oncogene. 2021 Sep;40(37):5651-5664. doi: 10.1038/s41388-021-01969-1. Epub 2021 Jul 29. Oncogene. 2021. PMID: 34326467 Free PMC article.
Mutations in ARL2BP, a protein required for ciliary microtubule structure, cause syndromic male infertility in humans and mice.
Moye AR, Bedoni N, Cunningham JG, Sanzhaeva U, Tucker ES, Mathers P, Peter VG, Quinodoz M, Paris LP, Coutinho-Santos L, Camacho P, Purcell MG, Winkelmann AC, Foster JA, Pugacheva EN, Rivolta C, Ramamurthy V. Moye AR, et al. Among authors: pugacheva en. PLoS Genet. 2019 Aug 19;15(8):e1008315. doi: 10.1371/journal.pgen.1008315. eCollection 2019 Aug. PLoS Genet. 2019. PMID: 31425546 Free PMC article.
47 results