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Page 1
Preclinical and clinical development of neoantigen vaccines.
Li L, Goedegebuure SP, Gillanders WE. Li L, et al. Among authors: goedegebuure sp. Ann Oncol. 2017 Dec 1;28(suppl_12):xii11-xii17. doi: 10.1093/annonc/mdx681. Ann Oncol. 2017. PMID: 29253113 Free PMC article. Review.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE. Li L, et al. Among authors: goedegebuure sp. Genome Med. 2021 Apr 21;13(1):56. doi: 10.1186/s13073-021-00872-4. Genome Med. 2021. PMID: 33879241 Free PMC article.
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.
Xia H, McMichael J, Becker-Hapak M, Onyeador OC, Buchli R, McClain E, Pence P, Supabphol S, Richters MM, Basu A, Ramirez CA, Puig-Saus C, Cotto KC, Freshour SL, Hundal J, Kiwala S, Goedegebuure SP, Johanns TM, Dunn GP, Ribas A, Miller CA, Gillanders WE, Fehniger TA, Griffith OL, Griffith M. Xia H, et al. Among authors: goedegebuure sp. Sci Immunol. 2023 Apr 14;8(82):eabg2200. doi: 10.1126/sciimmunol.abg2200. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027480 Free PMC article.
Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients.
Zhang X, Goedegebuure SP, Chen MY, Mishra R, Zhang F, Yu YY, Singhal K, Li L, Gao F, Myers NB, Vickery T, Hundal J, McLellan MD, Sturmoski MA, Kim SW, Chen I, Davidson JT 4th, Sankpal NV, Myles S, Suresh R, Ma CX, Foluso A, Wang-Gillam A, Davies S, Hagemann IS, Mardis ER, Griffith O, Griffith M, Miller CA, Hansen TH, Fleming TP, Schreiber RD, Gillanders WE. Zhang X, et al. Among authors: goedegebuure sp. Genome Med. 2024 Nov 14;16(1):131. doi: 10.1186/s13073-024-01388-3. Genome Med. 2024. PMID: 39538331 Free PMC article. Clinical Trial.
Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity.
Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, Miller CA, Ellis MJ, Mardis ER, Hansen T, Fleming TP, Goedegebuure SP, Gillanders WE. Zhang X, et al. Among authors: goedegebuure sp. Cancer Immunol Res. 2017 Jul;5(7):516-523. doi: 10.1158/2326-6066.CIR-16-0264. Epub 2017 Jun 15. Cancer Immunol Res. 2017. PMID: 28619968 Free PMC article.
Cancer vaccines: shared tumor antigens return to the spotlight.
Li L, Goedegebuure SP, Gillanders W. Li L, et al. Among authors: goedegebuure sp. Signal Transduct Target Ther. 2020 Oct 30;5(1):251. doi: 10.1038/s41392-020-00364-8. Signal Transduct Target Ther. 2020. PMID: 33127890 Free PMC article. No abstract available.
In silico epitope prediction analyses highlight the potential for distracting antigen immunodominance with allogeneic cancer vaccines.
James CA, Ronning P, Cullinan D, Cotto KC, Barnell EK, Campbell KM, Skidmore ZL, Sanford DE, Goedegebuure SP, Gillanders WE, Griffith OL, Hawkins WG, Griffith M. James CA, et al. Among authors: goedegebuure sp. Cancer Res Commun. 2021 Nov;1(2):115-126. doi: 10.1158/2767-9764.crc-21-0029. Cancer Res Commun. 2021. PMID: 35611186 Free PMC article.
55 results