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26 results

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Page 1
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Among authors: kernodle s. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. Nature. 2024. PMID: 39537932 Free PMC article.
Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons.
Zhang KX, D'Souza S, Upton BA, Kernodle S, Vemaraju S, Nayak G, Gaitonde KD, Holt AL, Linne CD, Smith AN, Petts NT, Batie M, Mukherjee R, Tiwari D, Buhr ED, Van Gelder RN, Gross C, Sweeney A, Sanchez-Gurmaches J, Seeley RJ, Lang RA. Zhang KX, et al. Among authors: kernodle s. Nature. 2020 Sep;585(7825):420-425. doi: 10.1038/s41586-020-2683-0. Epub 2020 Sep 2. Nature. 2020. PMID: 32879486 Free PMC article.
Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance.
Bozadjieva-Kramer N, Shin JH, Li Z, Rupp AC, Miller N, Kernodle S, Lanthier N, Henry P, Seshadri N, Myronovych A, MacDougald OA, O'Rourke RW, Kohli R, Burant CF, Rothberg AE, Seeley RJ. Bozadjieva-Kramer N, et al. Among authors: kernodle s. JCI Insight. 2024 Apr 8;9(7):e174164. doi: 10.1172/jci.insight.174164. JCI Insight. 2024. PMID: 38587078 Free PMC article.
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist.
Polex-Wolf J, Deibler K, Hogendorf WFJ, Bau S, Glendorf T, Stidsen CE, Tornøe CW, Tiantang D, Lundh S, Pyke C, Tomlinson AJ, Kernodle S, Magrisso IJ, Conde-Frieboes KW, Myers MG Jr, Knudsen LB, Seeley RJ. Polex-Wolf J, et al. Among authors: kernodle s. Sci Transl Med. 2024 Dec 4;16(776):eadk4908. doi: 10.1126/scitranslmed.adk4908. Epub 2024 Dec 4. Sci Transl Med. 2024. PMID: 39630884
Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP.
Wang Y, Qiu W, Kernodle S, Parker C, Padilla MA, Su J, Tomlinson AJ, Oldham S, Field J, Bernard E, Hornigold D, Rhodes CJ, Olson DP, Seeley RJ, Myers MG Jr. Wang Y, et al. Among authors: kernodle s. Mol Metab. 2025 Jan 2;92:102093. doi: 10.1016/j.molmet.2024.102093. Online ahead of print. Mol Metab. 2025. PMID: 39755369 Free article.
Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.
Nayak G, Zhang KX, Vemaraju S, Odaka Y, Buhr ED, Holt-Jones A, Kernodle S, Smith AN, Upton BA, D'Souza S, Zhan JJ, Diaz N, Nguyen MT, Mukherjee R, Gordon SA, Wu G, Schmidt R, Mei X, Petts NT, Batie M, Rao S, Hogenesch JB, Nakamura T, Sweeney A, Seeley RJ, Van Gelder RN, Sanchez-Gurmaches J, Lang RA. Nayak G, et al. Among authors: kernodle s. Cell Rep. 2020 Jan 21;30(3):672-686.e8. doi: 10.1016/j.celrep.2019.12.043. Cell Rep. 2020. PMID: 31968245 Free PMC article.
A Cross-Species Atlas of the Dorsal Vagal Complex Reveals Neural Mediators of Cagrilintide's Effects on Energy Balance.
Ludwig MQ, Coester B, Gordian D, Hassan S, Tomlinson AJ, Toure MH, Christensen OP, Moltke-Prehn A, Brown JM, Rausch DM, Gowda A, Wu I, Kernodle S, Dong V, Ayensu-Mensah M, Sabatini PV, Shin JH, Kirigiti M, Egerod KL, Le Foll C, Lundh S, Gerstenberg MK, Lutz TA, Kievit P, Secher A, Raun K, Myers MG, Pers TH. Ludwig MQ, et al. Among authors: kernodle s. bioRxiv [Preprint]. 2025 Jan 15:2025.01.13.632726. doi: 10.1101/2025.01.13.632726. bioRxiv. 2025. PMID: 39868309 Free PMC article. Preprint.
26 results