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ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization.
Zhang L, Cheng HH, Krüger N, Hörnich B, Graichen L, Hahn AS, Schulz SR, Jäck HM, Stankov MV, Behrens GMN, Müller MA, Drosten C, Mörer O, Winkler MS, Qian Z, Pöhlmann S, Hoffmann M. Zhang L, et al. Among authors: jack hm. PLoS Pathog. 2024 Nov 13;20(11):e1012653. doi: 10.1371/journal.ppat.1012653. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39536058 Free PMC article.
SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.
Zhang L, Kempf A, Nehlmeier I, Cossmann A, Richter A, Bdeir N, Graichen L, Moldenhauer AS, Dopfer-Jablonka A, Stankov MV, Simon-Loriere E, Schulz SR, Jäck HM, Čičin-Šain L, Behrens GMN, Drosten C, Hoffmann M, Pöhlmann S. Zhang L, et al. Among authors: jack hm. Cell. 2024 Feb 1;187(3):596-608.e17. doi: 10.1016/j.cell.2023.12.025. Epub 2024 Jan 8. Cell. 2024. PMID: 38194966
The effect of cilgavimab and neutralisation by vaccine-induced antibodies in emerging SARS-CoV-2 BA.4 and BA.5 sublineages.
Arora P, Zhang L, Nehlmeier I, Kempf A, Cossmann A, Dopfer-Jablonka A, Schulz SR, Jäck HM, Behrens GMN, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: jack hm. Lancet Infect Dis. 2022 Dec;22(12):1665-1666. doi: 10.1016/S1473-3099(22)00693-4. Epub 2022 Oct 31. Lancet Infect Dis. 2022. PMID: 36327999 Free PMC article. No abstract available.
Omicron sublineage BQ.1.1 resistance to monoclonal antibodies.
Arora P, Kempf A, Nehlmeier I, Schulz SR, Jäck HM, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: jack hm. Lancet Infect Dis. 2023 Jan;23(1):22-23. doi: 10.1016/S1473-3099(22)00733-2. Epub 2022 Nov 18. Lancet Infect Dis. 2023. PMID: 36410372 Free PMC article. No abstract available.
Neutralisation sensitivity of the SARS-CoV-2 XBB.1 lineage.
Arora P, Cossmann A, Schulz SR, Ramos GM, Stankov MV, Jäck HM, Behrens GMN, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: jack hm. Lancet Infect Dis. 2023 Feb;23(2):147-148. doi: 10.1016/S1473-3099(22)00831-3. Epub 2023 Jan 5. Lancet Infect Dis. 2023. PMID: 36620969 Free PMC article. No abstract available.
Neutralisation sensitivity of SARS-CoV-2 lineages EG.5.1 and XBB.2.3.
Zhang L, Kempf A, Nehlmeier I, Cossmann A, Dopfer-Jablonka A, Stankov MV, Schulz SR, Jäck HM, Behrens GMN, Pöhlmann S, Hoffmann M. Zhang L, et al. Among authors: jack hm. Lancet Infect Dis. 2023 Oct;23(10):e391-e392. doi: 10.1016/S1473-3099(23)00547-9. Epub 2023 Sep 13. Lancet Infect Dis. 2023. PMID: 37716358 No abstract available.
Genetic barrier to resistance: a critical parameter for efficacy of neutralizing monoclonal antibodies against SARS-CoV-2 in a nonhuman primate model.
Stahl-Hennig C, Peter AS, Cordsmeier A, Stolte-Leeb N, Vestweber R, Socher E, Merida SA, Sauermann U, Bleyer M, Fraedrich K, Grunwald T, Winkler TH, Ensser A, Jäck H-M, Überla K. Stahl-Hennig C, et al. J Virol. 2024 Jul 23;98(7):e0062824. doi: 10.1128/jvi.00628-24. Epub 2024 Jun 20. J Virol. 2024. PMID: 38899895 Free PMC article.
Identification of TFG- and Autophagy-Regulated Proteins and Glycerophospholipids in B Cells.
Steinmetz TD, Thomas J, Reimann L, Himmelreich AK, Schulz SR, Golombek F, Castiglione K, Jäck HM, Brodesser S, Warscheid B, Mielenz D. Steinmetz TD, et al. Among authors: jack hm. J Proteome Res. 2024 May 3;23(5):1615-1633. doi: 10.1021/acs.jproteome.3c00713. Epub 2024 Apr 22. J Proteome Res. 2024. PMID: 38649144 Free PMC article.
168 results