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Perfusion Process Intensification for Lentivirus Production Using a Novel Scale-Down Model.
Biotechnol Bioeng. 2025 Feb;122(2):344-360. doi: 10.1002/bit.28880. Epub 2024 Nov 13.
Biotechnol Bioeng. 2025.
PMID: 39535315
Free PMC article.
Generation of stable suspension producer cell lines for serum-free lentivirus production.
Klimpel M, Terrao M, Bräuer M, Dersch H, Biserni M, Melo Do Nascimento L, Schwingal S, Vogel JE, Ferlemann C, Brandt T, Lal NI, Bridgeman K, Petzke A, McDwyer E, Lim JL, Oh S, Brumatti G, Garcia Minambres A, Otte E, Noll T, Pirzas V, Laux H.
Klimpel M, et al. Among authors: pirzas v.
Biotechnol J. 2024 May;19(5):e2400090. doi: 10.1002/biot.202400090.
Biotechnol J. 2024.
PMID: 38719592
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High yield sterile filtration process for highly concentrated lentiviral vectors.
Vogel JE, Terrao M, Schwingal S, Kapitza L, Brigulla D, Pirzas V, Laux H, Brandt T.
Vogel JE, et al. Among authors: pirzas v.
Biotechnol J. 2024 Mar;19(3):e2300348. doi: 10.1002/biot.202300348.
Biotechnol J. 2024.
PMID: 38472091
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Development of a perfusion process for continuous lentivirus production using stable suspension producer cell lines.
Klimpel M, Terrao M, Ching N, Climenti V, Noll T, Pirzas V, Laux H.
Klimpel M, et al. Among authors: pirzas v.
Biotechnol Bioeng. 2023 Sep;120(9):2622-2638. doi: 10.1002/bit.28413. Epub 2023 May 6.
Biotechnol Bioeng. 2023.
PMID: 37148430
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