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canSAR 2024-an update to the public drug discovery knowledgebase.
Gingrich PW, Chitsazi R, Biswas A, Jiang C, Zhao L, Tym JE, Brammer KM, Li J, Shu Z, Maxwell DS, Tacy JA, Mica IL, Darkoh M, di Micco P, Russell KP, Workman P, Al-Lazikani B. Gingrich PW, et al. Among authors: chitsazi r. Nucleic Acids Res. 2025 Jan 6;53(D1):D1287-D1294. doi: 10.1093/nar/gkae1050. Nucleic Acids Res. 2025. PMID: 39535036 Free PMC article.
A subtle structural modification of a synthetic cannabinoid receptor agonist drastically increases its efficacy at the CB1 receptor.
Yano H, Chitsazi R, Lucaj C, Tran P, Hoffman AF, Baumann MH, Lupica CR, Shi L. Yano H, et al. Among authors: chitsazi r. bioRxiv [Preprint]. 2023 Jun 12:2023.06.10.544442. doi: 10.1101/2023.06.10.544442. bioRxiv. 2023. Update in: ACS Chem Neurosci. 2023 Nov 1;14(21):3928-3940. doi: 10.1021/acschemneuro.3c00530 PMID: 37398099 Free PMC article. Updated. Preprint.