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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy.
Cancer Cell. 2024 Nov 11;42(11):1955-1969.e7. doi: 10.1016/j.ccell.2024.10.009.
Cancer Cell. 2024.
PMID: 39532065
Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.
Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR.
Liu W, et al. Among authors: maestre if.
Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8.
Nat Cardiovasc Res. 2023.
PMID: 37539077
Free PMC article.
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Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma.
Van Haver S, Fan Y, Bekaert SL, Everaert C, Van Loocke W, Zanzani V, Deschildre J, Maestre IF, Amaro A, Vermeirssen V, De Preter K, Zhou T, Kentsis A, Studer L, Speleman F, Roberts SS.
Van Haver S, et al. Among authors: maestre if.
iScience. 2023 Sep 30;27(1):108096. doi: 10.1016/j.isci.2023.108096. eCollection 2024 Jan 19.
iScience. 2023.
PMID: 38222111
Free PMC article.
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Mesenchymal Stromal Cell Senescence Induced by Dnmt3a -Mutant Hematopoietic Cells is a Targetable Mechanism Driving Clonal Hematopoiesis and Initiation of Hematologic Malignancy.
Mistry JJ, Young KA, Colom Díaz PA, Maestre IF, Levine RL, Trowbridge JJ.
Mistry JJ, et al. Among authors: maestre if.
bioRxiv [Preprint]. 2024 Mar 30:2024.03.28.587254. doi: 10.1101/2024.03.28.587254.
bioRxiv. 2024.
PMID: 38585779
Free PMC article.
Preprint.
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