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Structural basis of the mechanism and inhibition of a human ceramide synthase.
Pascoa TC, Pike ACW, Tautermann CS, Chi G, Traub M, Quigley A, Chalk R, Štefanić S, Thamm S, Pautsch A, Carpenter EP, Schnapp G, Sauer DB. Pascoa TC, et al. Among authors: chi g. Nat Struct Mol Biol. 2024 Nov 11. doi: 10.1038/s41594-024-01414-3. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39528795
Protein Binder Toolbox for Studies of Solute Carrier Transporters.
Gelová Z, Ingles-Prieto A, Bohstedt T, Frommelt F, Chi G, Chang YN, Garcia J, Wolf G, Azzollini L, Tremolada S, Scacioc A, Hansen JS, Serrano I, Droce A, Bernal JC, Burgess-Brown NA, Carpenter EP, Dürr KL, Kristensen P, Geertsma ER, Štefanić S, Scarabottolo L, Wiedmer T, Puetter V, Sauer DB, Superti-Furga G. Gelová Z, et al. Among authors: chi g. J Mol Biol. 2024 Aug 15;436(16):168665. doi: 10.1016/j.jmb.2024.168665. Epub 2024 Jun 13. J Mol Biol. 2024. PMID: 38878854
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.
Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rödström KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB. Li HZ, et al. Among authors: chi g. Nat Commun. 2024 Jun 29;15(1):5503. doi: 10.1038/s41467-024-48921-x. Nat Commun. 2024. PMID: 38951531 Free PMC article.
High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies.
Raturi S, Li H, Chang YN, Scacioc A, Bohstedt T, Fernandez-Cid A, Evans A, Abrusci P, Balakrishnan A, Pascoa TC, He D, Chi G, Kaur Singh N, Ye M, Li A, Shrestha L, Wang D, Williams EP, Burgess-Brown NA, Dürr KL, Puetter V, Ingles-Prieto A, Sauer DB. Raturi S, et al. Among authors: chi g. J Vis Exp. 2023 Sep 29;(199). doi: 10.3791/65878. J Vis Exp. 2023. PMID: 37843272
The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Liang Q, Chi G, Cirqueira L, Zhi L, Marasco A, Pilati N, Gunthorpe MJ, Alvaro G, Large CH, Sauer DB, Treptow W, Covarrubias M. Liang Q, et al. Among authors: chi g. Nat Commun. 2024 Mar 21;15(1):2533. doi: 10.1038/s41467-024-46813-8. Nat Commun. 2024. PMID: 38514618 Free PMC article.
Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
Chi G, Jaślan D, Kudrina V, Böck J, Li H, Pike ACW, Rautenberg S, Krogsaeter E, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Mukhopadhyay SMM, Burgess-Brown NA, Keller M, Bracher F, Grimm C, Dürr KL. Chi G, et al. Structure. 2024 Aug 8;32(8):1137-1149.e4. doi: 10.1016/j.str.2024.05.005. Epub 2024 May 29. Structure. 2024. PMID: 38815576 Free PMC article.
Patient Preferences with Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema: A Multinational Discrete Choice Experiment Study.
García-Layana A, Chi GC, Kodjikian L, Parravano M, Chow D, Jackson TL, Danzig C, Paris LP, Mirt M, Henry-Szatkowski M, Lewis HB, Gentile B. García-Layana A, et al. Among authors: chi gc. Ophthalmic Res. 2025;68(1):13-22. doi: 10.1159/000541349. Epub 2024 Nov 21. Ophthalmic Res. 2025. PMID: 39571557 Free article.
485 results