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Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis.
Németh BZ, Demcsák A, Micsonai A, Kiss B, Schlosser G, Geisz A, Hegyi E, Sahin-Tóth M, Pál G. Németh BZ, et al. Biochim Biophys Acta Proteins Proteom. 2022 Sep 1;1870(9):140831. doi: 10.1016/j.bbapap.2022.140831. Epub 2022 Aug 5. Biochim Biophys Acta Proteins Proteom. 2022. PMID: 35934298 Free PMC article.