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Page 1
Dormancy-inducing 3D engineered matrix uncovers mechanosensitive and drug-protective FHL2-p21 signaling axis.
Bakhshandeh S, Heras U, Taïeb HM, Varadarajan AR, Lissek SM, Hücker SM, Lu X, Garske DS, Young SAE, Abaurrea A, Caffarel MM, Riestra A, Bragado P, Contzen J, Gossen M, Kirsch S, Warfsmann J, Honarnejad K, Klein CA, Cipitria A. Bakhshandeh S, et al. Among authors: varadarajan ar. Sci Adv. 2024 Nov 8;10(45):eadr3997. doi: 10.1126/sciadv.adr3997. Epub 2024 Nov 6. Sci Adv. 2024. PMID: 39504377 Free PMC article.
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients.
Stojanović Gužvić N, Lüke F, Treitschke S, Coluccio A, Hoffmann M, Feliciello G, Varadarajan AR, Lu X, Weidele K, Botteron C, Materna-Reichelt S, Keil F, Evert K, Weber F, Schamberger T, Althammer M, Grosse J, Hellwig D, Schulz C, Seitz S, Ugocsai P, Schlenska-Lange A, Mayr R, Kaiser U, Dietmaier W, Polzer B, Warfsmann J, Honarnejad K, Pukrop T, Heudobler D, Klein CA, Werno C. Stojanović Gužvić N, et al. Among authors: varadarajan ar. Mol Oncol. 2024 Oct 5. doi: 10.1002/1878-0261.13741. Online ahead of print. Mol Oncol. 2024. PMID: 39367702 Free article.
Ex vivo expansion of lung cancer-derived disseminated cancer cells from lymph nodes identifies cells associated with metastatic progression.
Treitschke S, Weidele K, Varadarajan AR, Feliciello G, Warfsmann J, Vorbeck S, Polzer B, Botteron C, Hoffmann M, Dechand V, Mederer T, Weber F, Werner-Klein M, Robold T, Hofmann HS, Werno C, Klein CA. Treitschke S, et al. Among authors: varadarajan ar. Int J Cancer. 2023 Nov 15;153(10):1854-1867. doi: 10.1002/ijc.34658. Epub 2023 Aug 9. Int J Cancer. 2023. PMID: 37555668
Hepatocellular Carcinoma in Mongolia Delineates Unique Molecular Traits and a Mutational Signature Associated with Environmental Agents.
Torrens L, Puigvehí M, Torres-Martín M, Wang H, Maeda M, Haber PK, Leonel T, García-López M, Esteban-Fabró R, Leow WQ, Montironi C, Torrecilla S, Varadarajan AR, Taik P, Campreciós G, Enkhbold C, Taivanbaatar E, Yerbolat A, Villanueva A, Pérez-Del-Pulgar S, Thung S, Chinburen J, Letouzé E, Zucman-Rossi J, Uzilov A, Neely J, Forns X, Roayaie S, Sia D, Llovet JM. Torrens L, et al. Among authors: varadarajan ar. Clin Cancer Res. 2022 Oct 14;28(20):4509-4520. doi: 10.1158/1078-0432.CCR-22-0632. Clin Cancer Res. 2022. PMID: 35998012 Free PMC article.
Phase II Clinical and Translational Study of Everolimus ± Paclitaxel as First-Line Therapy in Cisplatin-Ineligible Advanced Urothelial Carcinoma.
Jun T, Hahn NM, Sonpavde G, Albany C, MacVicar GR, Hauke R, Fleming M, Gourdin T, Jana B, Oh WK, Taik P, Wang H, Varadarajan AR, Uzilov A, Galsky MD. Jun T, et al. Among authors: varadarajan ar. Oncologist. 2022 Jun 8;27(6):432-e452. doi: 10.1093/oncolo/oyab075. Oncologist. 2022. PMID: 35438782 Free PMC article. Clinical Trial.
Tenomodulin knockout mice exhibit worse late healing outcomes with augmented trauma-induced heterotopic ossification of Achilles tendon.
Delgado Caceres M, Angerpointner K, Galler M, Lin D, Michel PA, Brochhausen C, Lu X, Varadarajan AR, Warfsmann J, Stange R, Alt V, Pfeifer CG, Docheva D. Delgado Caceres M, et al. Among authors: varadarajan ar. Cell Death Dis. 2021 Nov 5;12(11):1049. doi: 10.1038/s41419-021-04298-z. Cell Death Dis. 2021. PMID: 34741033 Free PMC article.
An integrated model system to gain mechanistic insights into biofilm-associated antimicrobial resistance in Pseudomonas aeruginosa MPAO1.
Varadarajan AR, Allan RN, Valentin JDP, Castañeda Ocampo OE, Somerville V, Pietsch F, Buhmann MT, West J, Skipp PJ, van der Mei HC, Ren Q, Schreiber F, Webb JS, Ahrens CH. Varadarajan AR, et al. NPJ Biofilms Microbiomes. 2020 Oct 30;6(1):46. doi: 10.1038/s41522-020-00154-8. NPJ Biofilms Microbiomes. 2020. PMID: 33127897 Free PMC article.
Optimized Proteomics Workflow for the Detection of Small Proteins.
Bartel J, Varadarajan AR, Sura T, Ahrens CH, Maaß S, Becher D. Bartel J, et al. Among authors: varadarajan ar. J Proteome Res. 2020 Oct 2;19(10):4004-4018. doi: 10.1021/acs.jproteome.0c00286. Epub 2020 Sep 2. J Proteome Res. 2020. PMID: 32812434
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