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Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment.
Zhou Y, Xu J, Hou Y, Leverenz JB, Kallianpur A, Mehra R, Liu Y, Yu H, Pieper AA, Jehi L, Cheng F. Zhou Y, et al. Among authors: pieper aa. bioRxiv [Preprint]. 2021 Mar 22:2021.03.15.435423. doi: 10.1101/2021.03.15.435423. bioRxiv. 2021. Update in: Alzheimers Res Ther. 2021 Jun 9;13(1):110. doi: 10.1186/s13195-021-00850-3 PMID: 33791705 Free PMC article. Updated. Preprint.
Network medicine informed multi-omics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis.
Yu M, Xu J, Dutta R, Trapp B, Pieper AA, Cheng F. Yu M, et al. Among authors: pieper aa. bioRxiv [Preprint]. 2024 Mar 30:2024.03.27.586949. doi: 10.1101/2024.03.27.586949. bioRxiv. 2024. Update in: NPJ Syst Biol Appl. 2024 Nov 5;10(1):128. doi: 10.1038/s41540-024-00449-y PMID: 38585774 Free PMC article. Updated. Preprint.
Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury.
Sridharan PS, Koh Y, Miller E, Hu D, Chakraborty S, Tripathi SJ, Kee TR, Chaubey K, Vázquez-Rosa E, Barker S, Liu H, León-Alvarado RA, Franke K, Cintrón-Pérez CJ, Dhar M, Shin MK, Flanagan ME, Castellani RJ, Gefen T, Bykova M, Dou L, Cheng F, Wilson BM, Fujioka H, Kang DE, Woo JA, Paul BD, Qi X, Pieper AA. Sridharan PS, et al. Among authors: pieper aa. Cell Rep Med. 2024 Sep 17;5(9):101715. doi: 10.1016/j.xcrm.2024.101715. Epub 2024 Sep 5. Cell Rep Med. 2024. PMID: 39241772 Free PMC article.
Single-microglia transcriptomic transition network-based prediction and real-world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease.
Xu J, Song W, Xu Z, Danziger MM, Karavani E, Zang C, Chen X, Li Y, Paz IMR, Gohel D, Su C, Zhou Y, Hou Y, Shimoni Y, Pieper AA, Hu J, Wang F, Rosen-Zvi M, Leverenz JB, Cummings J, Cheng F. Xu J, et al. Among authors: pieper aa. Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14373. Online ahead of print. Alzheimers Dement. 2024. PMID: 39641322
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[No authors listed] [No authors listed] PMID: 39750891
135 results