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LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endothelium.
Zhang H, Hansen M, Di Summa F, Von Lindern M, Gillemans N, Van IJcken WFJ, Svendsen AF, Philipsen S, Van der Reijden B, Varga E, Van den Akker E. Zhang H, et al. Among authors: van ijcken wfj. Haematologica. 2024 Dec 1;109(12):3975-3988. doi: 10.3324/haematol.2024.285214. Haematologica. 2024. PMID: 38961746 Free PMC article.
A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds.
Verheul TCJ, Gillemans N, Putzker K, Majied R, Li T, Vasiliou M, Eussen B, de Klein A, van IJcken WFJ, van den Akker E, von Lindern M, Lewis J, Uhrig U, Nakamura Y, van Dijk T, Philipsen S. Verheul TCJ, et al. Among authors: van ijcken wfj. Hemasphere. 2024 Aug 6;8(8):e139. doi: 10.1002/hem3.139. eCollection 2024 Aug. Hemasphere. 2024. PMID: 39108322 Free PMC article.
Bulk and single-cell transcriptomics identify gene signatures of stem cell-derived NK cell donors with superior cytolytic activity.
van Vliet AA, van den Hout MGCN, Steenmans D, Duru AD, Georgoudaki AM, de Gruijl TD, van IJcken WFJ, Spanholtz J, Raimo M. van Vliet AA, et al. Among authors: van ijcken wfj. Mol Ther Oncol. 2024 Sep 2;32(4):200870. doi: 10.1016/j.omton.2024.200870. eCollection 2024 Dec 19. Mol Ther Oncol. 2024. PMID: 39346765 Free PMC article.
Genome-wide analysis toward the epigenetic aetiology of myelodysplastic syndrome disease progression and pharmacoepigenomic basis of hypomethylating agents drug treatment response.
Siamoglou S, Boers R, Koromina M, Boers J, Tsironi A, Chatzilygeroudi T, Lazaris V, Verigou E, Kourakli A, van IJcken WFJ, Gribnau J, Symeonidis A, Patrinos GP. Siamoglou S, et al. Among authors: van ijcken wfj. Hum Genomics. 2023 Apr 25;17(1):37. doi: 10.1186/s40246-023-00483-7. Hum Genomics. 2023. PMID: 37098643 Free PMC article.
BMP4 and Temozolomide Synergize in the Majority of Patient-Derived Glioblastoma Cultures.
Verploegh ISC, Conidi A, El Hassnaoui H, Verhoeven FAM, Korporaal AL, Ntafoulis I, van den Hout MCGN, Brouwer RWW, Lamfers MLM, van IJcken WFJ, Huylebroeck D, Leenstra S. Verploegh ISC, et al. Among authors: van ijcken wfj. Int J Mol Sci. 2024 Sep 22;25(18):10176. doi: 10.3390/ijms251810176. Int J Mol Sci. 2024. PMID: 39337661 Free PMC article.
Human Pluripotent Stem Cell-Derived Astrocyte Functionality Compares Favorably with Primary Rat Astrocytes.
Lendemeijer B, Unkel M, Smeenk H, Mossink B, Hijazi S, Gordillo-Sampedro S, Shpak G, Slump DE, van den Hout MCGN, van IJcken WFJ, Bindels EMJ, Hoogendijk WJG, Nadif Kasri N, de Vrij FMS, Kushner SA. Lendemeijer B, et al. Among authors: van ijcken wfj. eNeuro. 2024 Sep 13;11(9):ENEURO.0148-24.2024. doi: 10.1523/ENEURO.0148-24.2024. Print 2024 Sep. eNeuro. 2024. PMID: 39227152 Free PMC article.
Epigenetic and Genomic Hallmarks of PARP-Inhibitor Resistance in Ovarian Cancer Patients.
Senturk Kirmizitas T, van den Berg C, Boers R, Helmijr J, Makrodimitris S, Dag HH, Kerkhofs M, Beaufort C, Kraan J, van IJcken WFJ, Gribnau J, Garkhail P, Boer GN, Roes EM, van Beekhuizen H, Gunel T, Wilting S, Martens J, Jansen M, Boere I. Senturk Kirmizitas T, et al. Among authors: van ijcken wfj. Genes (Basel). 2024 Jun 7;15(6):750. doi: 10.3390/genes15060750. Genes (Basel). 2024. PMID: 38927686 Free PMC article.
205 results