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Acanthamoeba castellanii trophozoites need oxygen for normal functioning and lipids are their preferred substrate, offering new possibilities for treatment.
Sarink MJ, Mykytyn AZ, Jedidi A, Houweling M, Brouwers JF, Ruijter G, Verbon A, van Hellemond JJ, Tielens AGM. Sarink MJ, et al. Among authors: tielens agm. Int J Parasitol. 2025 Jan;55(1):35-44. doi: 10.1016/j.ijpara.2024.10.004. Epub 2024 Oct 26. Int J Parasitol. 2025. PMID: 39490506 Free article.
The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host.
Bexkens ML, Martin OMF, van den Heuvel JM, Schmitz MGJ, Teusink B, Bakker BM, van Hellemond JJ, Haanstra JR, Walkinshaw MD, Tielens AGM. Bexkens ML, et al. Among authors: tielens agm. Int J Parasitol. 2024 Jun;54(7):367-378. doi: 10.1016/j.ijpara.2024.03.005. Epub 2024 Mar 15. Int J Parasitol. 2024. PMID: 38492780 Free article.
The decrease in plasma cholesterol during Plasmodium falciparum infections is not caused by cholesterol utilization by the parasites but by an infection-induced acute-phase response.
Vliegenthart-Jongbloed KJ, Koelewijn R, Tielens AGM, Sauerwein RW, van Hellemond JJ, van Genderen PJJ. Vliegenthart-Jongbloed KJ, et al. Among authors: tielens agm. J Infect. 2023 Jun;86(6):617-619. doi: 10.1016/j.jinf.2023.02.031. Epub 2023 Mar 2. J Infect. 2023. PMID: 36868319 No abstract available.
78 results