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Striving for balance in decisions on antenatal pharmacotherapy.
Koldeweij C, Jans VA, Waitt C, Greupink R, Auweele KLV, Franklin BD, Scheepers HC, de Wildt SN. Koldeweij C, et al. Among authors: de wildt sn. Lancet. 2024 Nov 2;404(10464):1779-1782. doi: 10.1016/S0140-6736(24)02069-5. Lancet. 2024. PMID: 39488410 Review.
Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review.
Stillhart C, Vučićević K, Augustijns P, Basit AW, Batchelor H, Flanagan TR, Gesquiere I, Greupink R, Keszthelyi D, Koskinen M, Madla CM, Matthys C, Miljuš G, Mooij MG, Parrott N, Ungell AL, de Wildt SN, Orlu M, Klein S, Müllertz A. Stillhart C, et al. Among authors: de wildt sn. Eur J Pharm Sci. 2020 Apr 30;147:105280. doi: 10.1016/j.ejps.2020.105280. Epub 2020 Feb 25. Eur J Pharm Sci. 2020. PMID: 32109493 Free article. Review.
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.
van der Heijden JEM, Freriksen JJM, de Hoop-Sommen MA, van Bussel LPM, Driessen SHP, Orlebeke AEM, Verscheijden LFM, Greupink R, de Wildt SN. van der Heijden JEM, et al. Among authors: de wildt sn, de hoop sommen ma. Clin Pharmacokinet. 2022 Dec;61(12):1705-1717. doi: 10.1007/s40262-022-01181-8. Epub 2022 Nov 11. Clin Pharmacokinet. 2022. PMID: 36369327 Free PMC article.
Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care.
van Borselen MD, Sluijterman LAÆ, Greupink R, de Wildt SN. van Borselen MD, et al. Among authors: de wildt sn. Clin Pharmacokinet. 2024 Mar;63(3):343-355. doi: 10.1007/s40262-023-01326-3. Epub 2024 Feb 15. Clin Pharmacokinet. 2024. PMID: 38361163 Free PMC article.
Optimization of the betamethasone and dexamethasone dosing regimen during pregnancy: a combined placenta perfusion and pregnancy physiologically based pharmacokinetic modeling approach.
Van Der Heijden JEM, Van Hove H, Van Elst NM, Van Den Broek P, Van Drongelen J, Scheepers HCJ, De Wildt SN, Greupink R. Van Der Heijden JEM, et al. Among authors: de wildt sn. Am J Obstet Gynecol. 2024 May 17:S0002-9378(24)00594-5. doi: 10.1016/j.ajog.2024.05.012. Online ahead of print. Am J Obstet Gynecol. 2024. PMID: 38763343 Free article.
Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept.
van der Heijden JEM, de Hoop-Sommen M, Hoevenaars N, Freriksen JJM, Joosten K, Greupink R, de Wildt SN. van der Heijden JEM, et al. Among authors: de wildt sn. Front Pediatr. 2024 Jul 5;12:1416440. doi: 10.3389/fped.2024.1416440. eCollection 2024. Front Pediatr. 2024. PMID: 39035463 Free PMC article.
253 results