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Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection.
Young MG, Straub TJ, Worby CJ, Metsky HC, Gnirke A, Bronson RA, van Dijk LR, Desjardins CA, Matranga C, Qu J, Villicana JB, Azimzadeh P, Kau A, Dodson KW, Schreiber HL 4th, Manson AL, Hultgren SJ, Earl AM. Young MG, et al. Among authors: kau a. Nat Commun. 2024 Nov 2;15(1):9466. doi: 10.1038/s41467-024-53829-7. Nat Commun. 2024. PMID: 39487120 Free PMC article.
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.
Spaulding CN, Klein RD, Ruer S, Kau AL, Schreiber HL, Cusumano ZT, Dodson KW, Pinkner JS, Fremont DH, Janetka JW, Remaut H, Gordon JI, Hultgren SJ. Spaulding CN, et al. Nature. 2017 Jun 22;546(7659):528-532. doi: 10.1038/nature22972. Epub 2017 Jun 14. Nature. 2017. PMID: 28614296 Free PMC article.
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women.
Worby CJ, Schreiber HL 4th, Straub TJ, van Dijk LR, Bronson RA, Olson BS, Pinkner JS, Obernuefemann CLP, Muñoz VL, Paharik AE, Azimzadeh PN, Walker BJ, Desjardins CA, Chou WC, Bergeron K, Chapman SB, Klim A, Manson AL, Hannan TJ, Hooton TM, Kau AL, Lai HH, Dodson KW, Hultgren SJ, Earl AM. Worby CJ, et al. Among authors: kau al. Nat Microbiol. 2022 May;7(5):630-639. doi: 10.1038/s41564-022-01107-x. Epub 2022 May 2. Nat Microbiol. 2022. PMID: 35505248 Free PMC article.
Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice.
Rosen AL, Lint MA, Voelker DH, Gilbert NM, Tomera CP, Santiago-Borges J, Wallace MA, Hannan TJ, Burnham CD, Hultgren SJ, Kau AL. Rosen AL, et al. Among authors: kau al. bioRxiv [Preprint]. 2023 Oct 13:2023.10.10.561753. doi: 10.1101/2023.10.10.561753. bioRxiv. 2023. Update in: mBio. 2024 Feb 14;15(2):e0255423. doi: 10.1128/mbio.02554-23 PMID: 37873489 Free PMC article. Updated. Preprint.
65 results