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Corrigendum to "Dissecting the Enterococcal Polysaccharide Antigen (EPA) structure to explore innate immune evasion and phage specificity" [Carbohydr. Polym. 347 (1 January 2025) 122686].
Davis JL, Norwood JS, Smith RE, O'Dea F, Chellappa K, Rowe ML, Williamson MP, Stafford GP, Vinogradov E, Maes E, Guérardel Y, Mesnage S. Davis JL, et al. Among authors: chellappa k. Carbohydr Polym. 2025 Feb 1;349(Pt A):122983. doi: 10.1016/j.carbpol.2024.122983. Epub 2024 Nov 18. Carbohydr Polym. 2025. PMID: 39643414 Free article. No abstract available.
Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner.
Kane AE, Chellappa K, Schultz MB, Arnold M, Li J, Amorim J, Diener C, Zhu D, Mitchell SJ, Griffin P, Tian X, Petty C, Conway R, Walsh K, Shelerud L, Duesing C, Mueller A, Li K, McNamara M, Shima RT, Mitchell J, Bonkowski MS, de Cabo R, Gibbons SM, Wu LE, Ikeno Y, Baur JA, Rajman L, Sinclair DA. Kane AE, et al. Among authors: chellappa k. bioRxiv [Preprint]. 2024 Jun 27:2024.06.21.599604. doi: 10.1101/2024.06.21.599604. bioRxiv. 2024. PMID: 38979132 Free PMC article. Preprint.
A subpopulation of lipogenic brown adipocytes drives thermogenic memory.
Lundgren P, Sharma PV, Dohnalová L, Coleman K, Uhr GT, Kircher S, Litichevskiy L, Bahnsen K, Descamps HC, Demetriadou C, Chan J, Chellappa K, Cox TO, Heyman Y, Pather SR, Shoffler C, Petucci C, Shalem O, Raj A, Baur JA, Snyder NW, Wellen KE, Levy M, Seale P, Li M, Thaiss CA. Lundgren P, et al. Among authors: chellappa k. Nat Metab. 2023 Oct;5(10):1691-1705. doi: 10.1038/s42255-023-00893-w. Epub 2023 Oct 2. Nat Metab. 2023. PMID: 37783943 Free PMC article.
A microbiome-dependent gut-brain pathway regulates motivation for exercise.
Dohnalová L, Lundgren P, Carty JRE, Goldstein N, Wenski SL, Nanudorn P, Thiengmag S, Huang KP, Litichevskiy L, Descamps HC, Chellappa K, Glassman A, Kessler S, Kim J, Cox TO, Dmitrieva-Posocco O, Wong AC, Allman EL, Ghosh S, Sharma N, Sengupta K, Cornes B, Dean N, Churchill GA, Khurana TS, Sellmyer MA, FitzGerald GA, Patterson AD, Baur JA, Alhadeff AL, Helfrich EJN, Levy M, Betley JN, Thaiss CA. Dohnalová L, et al. Among authors: chellappa k. Nature. 2022 Dec;612(7941):739-747. doi: 10.1038/s41586-022-05525-z. Epub 2022 Dec 14. Nature. 2022. PMID: 36517598 Free PMC article.
NAD precursors cycle between host tissues and the gut microbiome.
Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, Davidson SM, Thaiss CA, Migaud ME, Rabinowitz JD, Baur JA. Chellappa K, et al. Cell Metab. 2022 Dec 6;34(12):1947-1959.e5. doi: 10.1016/j.cmet.2022.11.004. Cell Metab. 2022. PMID: 36476934 Free PMC article.
Reducing NAD(H) to amplify rhythms.
Chellappa K, Baur JA. Chellappa K, et al. Nat Metab. 2021 Dec;3(12):1589-1590. doi: 10.1038/s42255-021-00494-5. Nat Metab. 2021. PMID: 34903882 No abstract available.
NAD+ flux is maintained in aged mice despite lower tissue concentrations.
McReynolds MR, Chellappa K, Chiles E, Jankowski C, Shen Y, Chen L, Descamps HC, Mukherjee S, Bhat YR, Lingala SR, Chu Q, Botolin P, Hayat F, Doke T, Susztak K, Thaiss CA, Lu W, Migaud ME, Su X, Rabinowitz JD, Baur JA. McReynolds MR, et al. Among authors: chellappa k. Cell Syst. 2021 Dec 15;12(12):1160-1172.e4. doi: 10.1016/j.cels.2021.09.001. Epub 2021 Sep 23. Cell Syst. 2021. PMID: 34559996 Free PMC article.
31 results