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All-trans retinoic acid-mediated ADAR1 degradation synergizes with PD-1 blockade to suppress pancreatic cancer.
Li CF, Bai LY, Wei Y, Lee HH, Yang R, Yao J, Wang H, Wang YN, Chang WC, Shen YC, Wang SC, Chou CW, Fu J, Ling J, Chu YY, Chiu CF, Wang M, Yu D, Chiao PJ, Liang H, Maitra A, Ying H, Hung MC. Li CF, et al. Among authors: chu yy. bioRxiv [Preprint]. 2024 Oct 23:2024.10.20.619300. doi: 10.1101/2024.10.20.619300. bioRxiv. 2024. PMID: 39484589 Free PMC article. Preprint.
Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex.
Chu YY, Chen MK, Wei Y, Lee HH, Xia W, Wang YN, Yam C, Hsu JL, Wang HL, Chang WC, Yamaguchi H, Jiang Z, Liu C, Li CF, Nie L, Chan LC, Gao Y, Wang SC, Liu J, Westin SN, Lee S, Sood AK, Yang L, Hortobagyi GN, Yu D, Hung MC. Chu YY, et al. Nat Cancer. 2022 Oct;3(10):1211-1227. doi: 10.1038/s43018-022-00438-2. Epub 2022 Oct 17. Nat Cancer. 2022. PMID: 36253486 Free PMC article.
Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer.
Cha JH, Chan LC, Wang YN, Chu YY, Wang CH, Lee HH, Xia W, Shyu WC, Liu SP, Yao J, Chang CW, Cheng FR, Liu J, Lim SO, Hsu JL, Yang WH, Hortobagyi GN, Lin C, Yang L, Yu D, Jeng LB, Hung MC. Cha JH, et al. Among authors: chu yy. J Biol Chem. 2022 Apr;298(4):101817. doi: 10.1016/j.jbc.2022.101817. Epub 2022 Mar 10. J Biol Chem. 2022. PMID: 35278434 Free PMC article.
Nuclear export signal mutation of epidermal growth factor receptor enhances malignant phenotypes of cancer cells.
Nie L, Wang YN, Hsu JM, Hou J, Chu YY, Chan LC, Huo L, Wei Y, Deng R, Tang J, Hsu YH, Ko HW, Lim SO, Huang K, Chen MK, Chiu TJ, Cheng CC, Fang YF, Li CW, Goverdhan A, Wu HJ, Lee CC, Wang WL, Hsu J, Chiao P, Wang SC, Hung MC. Nie L, et al. Among authors: chu yy. Am J Cancer Res. 2023 Apr 15;13(4):1209-1239. eCollection 2023. Am J Cancer Res. 2023. PMID: 37168336 Free PMC article.
185 results