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T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Bozkus CC, Brown M, Velazquez L, Thomas M, Wilson EA, O'Donnell T, Ruchnewitz D, Geertz D, Bykov Y, Kodysh J, Oguntuyo KY, Roudko V, Hoyos D, Srivastava KD, Kleiner G, Alshammary H, Karekar N, McClain C, Gopal R, Nie K, Del Valle D, Delbeau-Zagelbaum D, Rodriguez D, Setal J; Mount Sinai COVID-19 Biobank Team; Carroll E, Wiesendanger M, Gulko PS, Charney A, Merad M, Kim-Schulze S, Lee B, Wajnberg A, Simon V, Greenbaum BD, Chowell D, Vabret N, Luksza M, Bhardwaj N. Bozkus CC, et al. Among authors: mcclain c. bioRxiv [Preprint]. 2024 Oct 24:2024.10.23.619918. doi: 10.1101/2024.10.23.619918. bioRxiv. 2024. PMID: 39484455 Free PMC article. Preprint.
SARS-CoV-2: the many pros of targeting PLpro.
McClain CB, Vabret N. McClain CB, et al. Signal Transduct Target Ther. 2020 Oct 6;5(1):223. doi: 10.1038/s41392-020-00335-z. Signal Transduct Target Ther. 2020. PMID: 33024071 Free PMC article. No abstract available.
Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
Roudko V, Bozkus CC, Orfanelli T, McClain CB, Carr C, O'Donnell T, Chakraborty L, Samstein R, Huang KL, Blank SV, Greenbaum B, Bhardwaj N. Roudko V, et al. Among authors: mcclain cb. Cell. 2020 Dec 10;183(6):1634-1649.e17. doi: 10.1016/j.cell.2020.11.004. Epub 2020 Nov 30. Cell. 2020. PMID: 33259803 Free PMC article.
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.
Vabret N, Najburg V, Solovyov A, Gopal R, McClain C, Šulc P, Balan S, Rahou Y, Beauclair G, Chazal M, Varet H, Legendre R, Sismeiro O, Sanchez David RY, Chauveau L, Jouvenet N, Markowitz M, van der Werf S, Schwartz O, Tangy F, Bhardwaj N, Greenbaum BD, Komarova AV. Vabret N, et al. Among authors: mcclain c. iScience. 2022 Jun 11;25(7):104599. doi: 10.1016/j.isci.2022.104599. eCollection 2022 Jul 15. iScience. 2022. PMID: 35789859 Free PMC article.
Combined Vaccination with NY-ESO-1 Protein, Poly-ICLC, and Montanide Improves Humoral and Cellular Immune Responses in Patients with High-Risk Melanoma.
Pavlick A, Blazquez AB, Meseck M, Lattanzi M, Ott PA, Marron TU, Holman RM, Mandeli J, Salazar AM, McClain CB, Gimenez G, Balan S, Gnjatic S, Sabado RL, Bhardwaj N. Pavlick A, et al. Cancer Immunol Res. 2020 Jan;8(1):70-80. doi: 10.1158/2326-6066.CIR-19-0545. Epub 2019 Nov 7. Cancer Immunol Res. 2020. PMID: 31699709 Free PMC article. Clinical Trial.
Impact of chronic ethanol consumption and SARS-COV-2 on the liver and intestine: A pilot dose-response study in mice.
Ghare S, Warner D, Warner J, Chilton PM, Lee J, Zhang J, Wang M, Hardesty J, Treves R, Gabbard J, Anderson C, Batra L, Sreenivasan C, Kraenzle J, McCulley M, McCoy S, Zhang L, Feng W, Gondim DD, Barve S, Zheng J, Palmer K, McClain C, Kirpich I. Ghare S, et al. Among authors: mcclain c. Alcohol Clin Exp Res (Hoboken). 2025 Jan 5. doi: 10.1111/acer.15528. Online ahead of print. Alcohol Clin Exp Res (Hoboken). 2025. PMID: 39757351
Visium spatial transcriptomics and proteomics identifies novel hepatic cell populations and transcriptomic signatures of alcohol-associated hepatitis.
Gripshover TC, Treves RS, Rouchka EC, Chariker JH, Zheng S, Hudson E, Smith ML, Singal AK, McClain CJ, Hardesty JE. Gripshover TC, et al. Among authors: mcclain cj. Alcohol Clin Exp Res (Hoboken). 2025 Jan;49(1):106-116. doi: 10.1111/acer.15494. Epub 2024 Nov 26. Alcohol Clin Exp Res (Hoboken). 2025. PMID: 39592394
829 results