Georgey HH - Search Results

1

Discovery of pyrazole-based analogs as CDK2 inhibitors with apoptotic-inducing activity: design, synthesis and molecular dynamics study.

Ali GME, Ewida MA, Elmetwali AM, Ewida HA, George RF, Mahmoud WR, Ismail NSM, Ahmed MS, Georgey HH. Ali GME, et al. Among authors: georgey hh. RSC Adv. 2024 Oct 29;14(47):34537-34555. doi: 10.1039/d4ra06500j. eCollection 2024 Oct 29. RSC Adv. 2024. PMID: 39479486 Free PMC article.

2

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors.

El-Gazzar YI, Georgey HH, El-Messery SM, Ewida HA, Hassan GS, Raafat MM, Ewida MA, El-Subbagh HI. El-Gazzar YI, et al. Among authors: georgey hh. Bioorg Chem. 2017 Jun;72:282-292. doi: 10.1016/j.bioorg.2017.04.019. Epub 2017 May 4. Bioorg Chem. 2017. PMID: 28499189

3

Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.

Hassan GS, Georgey HH, Mohammed EZ, George RF, Mahmoud WR, Omar FA. Hassan GS, et al. Among authors: georgey hh. Eur J Med Chem. 2021 Jun 5;218:113389. doi: 10.1016/j.ejmech.2021.113389. Epub 2021 Mar 18. Eur J Med Chem. 2021. PMID: 33784602

4

Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors.

Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI. Ewida MA, et al. Among authors: georgey hh. Arch Pharm (Weinheim). 2021 Nov;354(11):e2100202. doi: 10.1002/ardp.202100202. Epub 2021 Jul 27. Arch Pharm (Weinheim). 2021. PMID: 34313342

5

3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations.

Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI. Ewida MA, et al. Among authors: georgey hh. Bioorg Chem. 2021 Oct;115:105205. doi: 10.1016/j.bioorg.2021.105205. Epub 2021 Jul 24. Bioorg Chem. 2021. PMID: 34329992

6

Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).

Mohammed EZ, Mahmoud WR, George RF, Hassan GS, Omar FA, Georgey HH. Mohammed EZ, et al. Among authors: georgey hh. Bioorg Chem. 2021 Nov;116:105347. doi: 10.1016/j.bioorg.2021.105347. Epub 2021 Sep 11. Bioorg Chem. 2021. PMID: 34555628

7

Bacterial virulence factors: a target for heterocyclic compounds to combat bacterial resistance.

Abd El-Aleam RH, George RF, Georgey HH, Abdel-Rahman HM. Abd El-Aleam RH, et al. Among authors: georgey hh. RSC Adv. 2021 Nov 19;11(58):36459-36482. doi: 10.1039/d1ra06238g. eCollection 2021 Nov 10. RSC Adv. 2021. PMID: 35494393 Free PMC article. Review.

8

Insight on Some Newly Synthesized Trisubstituted Imidazolinones as VEGFR-2 Inhibitors.

Mohamed MR, Mahmoud WR, Refaey RH, George RF, Georgey HH. Mohamed MR, et al. Among authors: georgey hh. ACS Med Chem Lett. 2024 May 29;15(6):892-898. doi: 10.1021/acsmedchemlett.4c00095. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894896

9

Identification of some novel xanthine-based derivatives with bronchodilator activity.

Mohamed AR, Georgey HH, George RF, El-Eraky WI, Saleh DO, Abdel Gawad NM. Mohamed AR, et al. Among authors: georgey hh. Future Med Chem. 2017 Oct;9(15):1731-1747. doi: 10.4155/fmc-2017-0092. Epub 2017 Sep 5. Future Med Chem. 2017. PMID: 28871831

10

Construction of some cytotoxic agents with aurone and furoaurone scaffolds.

Hassan GS, Georgey HH, George RF, Mohammed ER. Hassan GS, et al. Among authors: georgey hh. Future Med Chem. 2018 Jan;10(1):27-52. doi: 10.4155/fmc-2017-0147. Epub 2017 Dec 13. Future Med Chem. 2018. PMID: 29235893

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