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Page 1
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis.
Douglas A, Stevens B, Rendas M, Kane H, Lynch E, Kunkemoeller B, Wessendorf-Rodriguez K, Day EA, Sutton C, Brennan M, O'Brien K, Kohlgruber AC, Prendeville H, Garza AE, O'Neill LAJ, Mills KHG, Metallo CM, Veiga-Fernandes H, Lynch L. Douglas A, et al. Among authors: day ea. Nature. 2024 Dec;636(8041):206-214. doi: 10.1038/s41586-024-08131-3. Epub 2024 Oct 30. Nature. 2024. PMID: 39478228 Free PMC article.
Targeting mitochondria to beat HIV-1.
Day EA, O'Neill LAJ. Day EA, et al. Nat Immunol. 2021 Apr;22(4):398-399. doi: 10.1038/s41590-021-00881-w. Nat Immunol. 2021. PMID: 33767428 No abstract available.
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Hooftman A, et al. Among authors: day ea. Nature. 2023 Mar;615(7952):490-498. doi: 10.1038/s41586-023-05720-6. Epub 2023 Mar 8. Nature. 2023. PMID: 36890227 Free PMC article.
The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, Lopes NP, Cunha FQ, O'Neill LAJ, Alves-Filho JC. Toller-Kawahisa JE, et al. Among authors: day ea. Nat Commun. 2023 Jul 17;14(1):4280. doi: 10.1038/s41467-023-40021-6. Nat Commun. 2023. PMID: 37460614 Free PMC article.
Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
O'Carroll SM, Peace CG, Toller-Kawahisa JE, Min Y, Hooftman A, Charki S, Kehoe L, O'Sullivan MJ, Zoller A, Mcgettrick AF, Zotta A, Day EA, Simarro M, Armstrong N, Annes JP, O'Neill LAJ. O'Carroll SM, et al. Among authors: day ea. Nat Metab. 2024 Nov;6(11):2060-2069. doi: 10.1038/s42255-024-01145-1. Epub 2024 Oct 15. Nat Metab. 2024. PMID: 39406969
Author Correction: Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
O'Carroll SM, Peace CG, Toller-Kawahisa JE, Min Y, Hooftman A, Charki S, Kehoe L, O'Sullivan MJ, Zoller A, Mcgettrick AF, Zotta A, Day EA, Simarro M, Armstrong N, Annes JP, O'Neill LAJ. O'Carroll SM, et al. Among authors: day ea. Nat Metab. 2024 Dec 12. doi: 10.1038/s42255-024-01204-7. Online ahead of print. Nat Metab. 2024. PMID: 39668260 No abstract available.
71 results