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232 results

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Page 1
Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas.
Chen J, Sobecki M, Krzywinska E, Thierry K, Masmoudi M, Nagarajan S, Fan Z, He J, Ferapontova I, Nelius E, Seehusen F, Gotthardt D, Takeda N, Sommer L, Sexl V, Münz C, DeNardo D, Hennino A, Stockmann C. Chen J, et al. Among authors: denardo d. EMBO Mol Med. 2024 Dec;16(12):3033-3056. doi: 10.1038/s44321-024-00157-4. Epub 2024 Oct 30. EMBO Mol Med. 2024. PMID: 39478152 Free PMC article.
Chemokine Receptor 2 Targeted PET/CT Imaging Distant Metastases in Pancreatic Ductal Adenocarcinoma.
Zhang X, Detering L, Heo GS, Sultan D, Luehmann H, Li L, Somani V, Lesser J, Tao J, Kang LI, Li A, Lahad D, Rho S, Ruzinova MB, DeNardo DG, Dehdashti F, Lim KH, Liu Y. Zhang X, et al. Among authors: denardo dg. ACS Pharmacol Transl Sci. 2023 Dec 5;7(1):285-293. doi: 10.1021/acsptsci.3c00303. eCollection 2024 Jan 12. ACS Pharmacol Transl Sci. 2023. PMID: 38230294 Free PMC article.
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
Panni UY, Chen MY, Zhang F, Cullinan DR, Li L, James CA, Zhang X, Rogers S, Alarcon A, Baer JM, Zhang D, Gao F, Miller CA, Gong Q, Lim KH, DeNardo DG, Goedegebuure SP, Gillanders WE, Hawkins WG. Panni UY, et al. Among authors: denardo dg. Cancer Immunol Immunother. 2023 Aug;72(8):2813-2827. doi: 10.1007/s00262-023-03463-x. Epub 2023 May 13. Cancer Immunol Immunother. 2023. PMID: 37179276 Free PMC article.
High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival.
Storrs EP, Chati P, Usmani A, Sloan I, Krasnick BA, Babbra R, Harris PK, Sachs CM, Qaium F, Chatterjee D, Wetzel C, Goedegebuure SP, Hollander T, Anthony H, Ponce J, Khaliq AM, Badiyan S, Kim H, Denardo DG, Lang GD, Cosgrove ND, Kushnir VM, Early DS, Masood A, Lim KH, Hawkins WG, Ding L, Fields RC, Das KK, Chaudhuri AA. Storrs EP, et al. Among authors: denardo dg. NPJ Precis Oncol. 2023 Oct 19;7(1):105. doi: 10.1038/s41698-023-00455-z. NPJ Precis Oncol. 2023. PMID: 37857854 Free PMC article.
Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction.
Selli ME, Landmann JH, Terekhova M, Lattin J, Heard A, Hsu YS, Chang TC, Chang J, Warrington J, Ha H, Kingston N, Hogg G, Slade M, Berrien-Elliott MM, Foster M, Kersting-Schadek S, Gruszczynska A, DeNardo D, Fehniger TA, Artyomov M, Singh N. Selli ME, et al. Among authors: denardo d. Blood. 2023 Jun 29;141(26):3153-3165. doi: 10.1182/blood.2023020100. Blood. 2023. PMID: 37130030 Free PMC article.
HMGA2 Expression Predicts Subtype, Survival, and Treatment Outcome in Pancreatic Ductal Adenocarcinoma.
Yamamoto N, Dobersch S, Loveless I, Samraj AN, Jang GH, Haraguchi M, Kang LI, Ruzinova MB, Vij KR, Mudd JL, Walsh T, Safyan RA, Chiorean EG, Hingorani SR, Bolton NM, Li L, Fields RC, DeNardo DG, Notta F, Crawford HC, Steele NG, Kugel S. Yamamoto N, et al. Among authors: denardo dg. Clin Cancer Res. 2024 Dec 16. doi: 10.1158/1078-0432.CCR-24-2200. Online ahead of print. Clin Cancer Res. 2024. PMID: 39680021
Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity.
Hänggi K, Li J, Gangadharan A, Liu X, Celias DP, Osunmakinde O, Keske A, Davis J, Ahmad F, Giron A, Anadon CM, Gardner A, DeNardo DG, Shaw TI, Beg AA, Yu X, Ruffell B. Hänggi K, et al. Among authors: denardo dg. Cancer Cell. 2024 Dec 9;42(12):2015-2031.e11. doi: 10.1016/j.ccell.2024.10.014. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577420
Stromal reprogramming overcomes resistance to RAS-MAPK inhibition to improve pancreas cancer responses to cytotoxic and immune therapy.
Liu X, Baer JM, Stone ML, Knolhoff BL, Hogg GD, Turner MC, Kao YL, Weinstein AG, Ahmad F, Chen J, Schmidt AD, Klomp JA, Coho H, Coho KS, Coma S, Pachter JA, Bryant KL, Kang LI, Lim KH, Beatty GL, DeNardo DG. Liu X, et al. Among authors: denardo dg. Sci Transl Med. 2024 Oct 23;16(770):eado2402. doi: 10.1126/scitranslmed.ado2402. Epub 2024 Oct 23. Sci Transl Med. 2024. PMID: 39441902
232 results