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Page 1
Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture.
Pourmal S, Truong ME, Johnson MC, Yang Y, Zhou L, Alegre K, Stowe IB, Gupta S, Chen PA, Zhang Y, Rohou A, Newton K, Kayagaki N, Dixit VM, Deshpande I. Pourmal S, et al. Among authors: rohou a. Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08273-4. Online ahead of print. Nature. 2024. PMID: 39476863
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge.
Lawson CL, Kryshtafovych A, Pintilie GD, Burley SK, Černý J, Chen VB, Emsley P, Gobbi A, Joachimiak A, Noreng S, Prisant MG, Read RJ, Richardson JS, Rohou AL, Schneider B, Sellers BD, Shao C, Sourial E, Williams CI, Williams CJ, Yang Y, Abbaraju V, Afonine PV, Baker ML, Bond PS, Blundell TL, Burnley T, Campbell A, Cao R, Cheng J, Chojnowski G, Cowtan KD, DiMaio F, Esmaeeli R, Giri N, Grubmüller H, Hoh SW, Hou J, Hryc CF, Hunte C, Igaev M, Joseph AP, Kao WC, Kihara D, Kumar D, Lang L, Lin S, Maddhuri Venkata Subramaniya SR, Mittal S, Mondal A, Moriarty NW, Muenks A, Murshudov GN, Nicholls RA, Olek M, Palmer CM, Perez A, Pohjolainen E, Pothula KR, Rowley CN, Sarkar D, Schäfer LU, Schlicksup CJ, Schröder GF, Shekhar M, Si D, Singharoy A, Sobolev OV, Terashi G, Vaiana AC, Vedithi SC, Verburgt J, Wang X, Warshamanage R, Winn MD, Weyand S, Yamashita K, Zhao M, Schmid MF, Berman HM, Chiu W. Lawson CL, et al. Among authors: rohou al. Nat Methods. 2024 Jul;21(7):1340-1348. doi: 10.1038/s41592-024-02321-7. Epub 2024 Jun 25. Nat Methods. 2024. PMID: 38918604
Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.
Kschonsak M, Rougé L, Arthur CP, Hoangdung H, Patel N, Kim I, Johnson MC, Kraft E, Rohou AL, Gill A, Martinez-Martin N, Payandeh J, Ciferri C. Kschonsak M, et al. Among authors: rohou al. Cell. 2021 Mar 4;184(5):1232-1244.e16. doi: 10.1016/j.cell.2021.01.036. Epub 2021 Feb 23. Cell. 2021. PMID: 33626330 Free article.
Improving cryo-EM structure validation.
Rohou A. Rohou A. Nat Methods. 2021 Feb;18(2):130-131. doi: 10.1038/s41592-021-01062-1. Nat Methods. 2021. PMID: 33542515 No abstract available.
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Kschonsak M, Johnson MC, Schelling R, Green EM, Rougé L, Ho H, Patel N, Kilic C, Kraft E, Arthur CP, Rohou AL, Comps-Agrar L, Martinez-Martin N, Perez L, Payandeh J, Ciferri C. Kschonsak M, et al. Sci Adv. 2022 Mar 11;8(10):eabm2536. doi: 10.1126/sciadv.abm2536. Epub 2022 Mar 11. Sci Adv. 2022. PMID: 35275719 Free PMC article.
Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase.
Mazhab-Jafari MT, Rohou A, Schmidt C, Bueler SA, Benlekbir S, Robinson CV, Rubinstein JL. Mazhab-Jafari MT, et al. Among authors: rohou a. Nature. 2016 Nov 3;539(7627):118-122. doi: 10.1038/nature19828. Epub 2016 Oct 24. Nature. 2016. PMID: 27776355 Free PMC article.
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy.
Terrett JA, Chen H, Shore DG, Villemure E, Larouche-Gauthier R, Déry M, Beaumier F, Constantineau-Forget L, Grand-Maître C, Lépissier L, Ciblat S, Sturino C, Chen Y, Hu B, Lu A, Wang Y, Cridland AP, Ward SI, Hackos DH, Reese RM, Shields SD, Chen J, Balestrini A, Riol-Blanco L, Lee WP, Liu J, Suto E, Wu X, Zhang J, Ly JQ, La H, Johnson K, Baumgardner M, Chou KJ, Rohou A, Rougé L, Safina BS, Magnuson S, Volgraf M. Terrett JA, et al. Among authors: rohou a. J Med Chem. 2021 Apr 8;64(7):3843-3869. doi: 10.1021/acs.jmedchem.0c02023. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33749283
36 results