Le W - Search Results

1

Amyloid fibril structures and ferroptosis activation induced by ALS-causing SOD1 mutations.

Wang LQ, Ma Y, Zhang MY, Yuan HY, Li XN, Xia W, Zhao K, Huang X, Chen J, Li D, Zou L, Wang Z, Le W, Liu C, Liang Y. Wang LQ, et al. Among authors: le w. Sci Adv. 2024 Nov;10(44):eado8499. doi: 10.1126/sciadv.ado8499. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475611 Free PMC article.

2

Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.

Li X, Zhang S, Liu Z, Tao Y, Xia W, Sun Y, Liu C, Le W, Sun B, Li D. Li X, et al. Among authors: le w. iScience. 2022 Nov 22;25(12):105645. doi: 10.1016/j.isci.2022.105645. eCollection 2022 Dec 22. iScience. 2022. PMID: 36505939 Free PMC article.

3

A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain.

Zhao Q, Fan Y, Zhao W, Ni Y, Tao Y, Bian J, Xia W, Yu W, Fan Z, Liu C, Sun B, Le W, Li W, Wang J, Li D. Zhao Q, et al. Among authors: le w. Cell Discov. 2024 May 14;10(1):50. doi: 10.1038/s41421-024-00674-z. Cell Discov. 2024. PMID: 38744856 Free PMC article. No abstract available.

4

Different charged biopolymers induce α-synuclein to form fibrils with distinct structures.

Yao Y, Zhao Q, Tao Y, Liu K, Cao T, Chen Z, Liu C, Le W, Zhao J, Li D, Kang W. Yao Y, et al. Among authors: le w. J Biol Chem. 2024 Nov;300(11):107862. doi: 10.1016/j.jbc.2024.107862. Epub 2024 Oct 5. J Biol Chem. 2024. PMID: 39374778 Free PMC article.

5

Integrated cerebellar radiomic-network model for predicting mild cognitive impairment in Alzheimer's disease.

Chen Y, Qi Y, Hu Y, Qiu X, Qiu T, Li S, Liu M, Jia Q, Sun B, Liu C, Li T, Le W; Alzheimer's Disease Neuroimaging Initiative. Chen Y, et al. Among authors: le w. Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14361. Online ahead of print. Alzheimers Dement. 2024. PMID: 39535490

6

Integrative analysis of metabolomics and proteomics unravels purine metabolism dysregulation in the SOD1^G93A mouse model of amyotrophic lateral sclerosis.

Xu X, Yang Q, Liu Z, Zhang R, Yu H, Wang M, Chen S, Xu G, Shao Y, Le W. Xu X, et al. Among authors: le w. Neurobiol Dis. 2023 Jun 1;181:106110. doi: 10.1016/j.nbd.2023.106110. Epub 2023 Mar 29. Neurobiol Dis. 2023. PMID: 37001614 Free article.

7

PM2.5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62-KEAP1-NRF2 activation in neuronal cells.

Wei M, Bao G, Li S, Yang Z, Cheng C, Le W. Wei M, et al. Among authors: le w. Ecotoxicol Environ Saf. 2022 Dec 15;248:114333. doi: 10.1016/j.ecoenv.2022.114333. Epub 2022 Nov 26. Ecotoxicol Environ Saf. 2022. PMID: 36446170 Free article.

8

Chronic Sleep Disturbances Alters Sleep Structure and Tau Phosphorylation in AβPP/PS1 AD Mice and Their Wild-Type Littermates.

Zhang F, Niu L, Zhong R, Li S, Le W. Zhang F, et al. Among authors: le w. J Alzheimers Dis. 2023;92(4):1341-1355. doi: 10.3233/JAD-221048. J Alzheimers Dis. 2023. PMID: 37038814

9

The electrophysiological and neuropathological profiles of cerebellum in APP^swe /PS1^ΔE9 mice: A hypothesis on the role of cerebellum in Alzheimer's disease.

Yu H, Wang M, Yang Q, Xu X, Zhang R, Chen X, Le W. Yu H, et al. Among authors: le w. Alzheimers Dement. 2023 Jun;19(6):2365-2375. doi: 10.1002/alz.12853. Epub 2022 Dec 5. Alzheimers Dement. 2023. PMID: 36469008

10

Oxygen metabolism abnormality and Alzheimer's disease: An update.

Liu G, Yang C, Wang X, Chen X, Wang Y, Le W. Liu G, et al. Among authors: le w. Redox Biol. 2023 Dec;68:102955. doi: 10.1016/j.redox.2023.102955. Epub 2023 Nov 8. Redox Biol. 2023. PMID: 37956598 Free PMC article. Review.

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