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Caspase-2 kills cells with extra centrosomes.
Rizzotto D, Vigorito V, Rieder P, Gallob F, Moretta GM, Soratroi C, Riley JS, Bellutti F, Veli SL, Mattivi A, Lohmüller M, Herzog S, Bornhauser BC, Jacotot ED, Villunger A, Fava LL. Rizzotto D, et al. Among authors: bornhauser bc. Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475598 Free PMC article.
Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling.
Seyfried F, Demir S, Hörl RL, Stirnweiß FU, Ryan J, Scheffold A, Villalobos-Ortiz M, Boldrin E, Zinngrebe J, Enzenmüller S, Jenni S, Tsai YC, Bornhauser B, Fürstberger A, Kraus JM, Kestler HA, Bourquin JP, Stilgenbauer S, Letai A, Debatin KM, Meyer LH. Seyfried F, et al. Cell Death Dis. 2019 Jul 29;10(8):571. doi: 10.1038/s41419-019-1801-0. Cell Death Dis. 2019. PMID: 31358732 Free PMC article.
TNFR2 is required for RIP1-dependent cell death in human leukemia.
Aguadé-Gorgorió J, McComb S, Eckert C, Guinot A, Marovca B, Mezzatesta C, Jenni S, Abduli L, Schrappe M, Dobay MP, Stanulla M, von Stackelberg A, Cario G, Bourquin JP, Bornhauser BC. Aguadé-Gorgorió J, et al. Among authors: bornhauser bc. Blood Adv. 2020 Oct 13;4(19):4823-4833. doi: 10.1182/bloodadvances.2019000796. Blood Adv. 2020. PMID: 33027529 Free PMC article.
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets.
Hoell JI, Ginzel S, Kuhlen M, Kloetgen A, Gombert M, Fischer U, Hein D, Demir S, Stanulla M, Schrappe M, Zur Stadt U, Bader P, Babor F, Schuster F, Strahm B, Alten J, Moericke A, Escherich G, von Stackelberg A, Thiele R, McHardy AC, Peters C, Bornhauser B, Bourquin JP, Krause S, Enczmann J, Meyer LH, Eckert C, Borkhardt A, Meisel R. Hoell JI, et al. Blood Adv. 2019 Oct 22;3(20):3143-3156. doi: 10.1182/bloodadvances.2019000051. Blood Adv. 2019. PMID: 31648313 Free PMC article.
Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia.
Mezzatesta C, Bornhauser BC. Mezzatesta C, et al. Among authors: bornhauser bc. Front Cell Dev Biol. 2019 Mar 19;7:40. doi: 10.3389/fcell.2019.00040. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 30941349 Free PMC article. Review.
48 results