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Page 1
Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.
Gomes LA, Hipp SA, Rijal Upadhaya A, Balakrishnan K, Ospitalieri S, Koper MJ, Largo-Barrientos P, Uytterhoeven V, Reichwald J, Rabe S, Vandenberghe R, von Arnim CAF, Tousseyn T, Feederle R, Giudici C, Willem M, Staufenbiel M, Thal DR. Gomes LA, et al. Among authors: staufenbiel m. Acta Neuropathol. 2019 Dec;138(6):913-941. doi: 10.1007/s00401-019-02053-5. Epub 2019 Aug 14. Acta Neuropathol. 2019. PMID: 31414210
Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.
Abramowski D, Rabe S, Upadhaya AR, Reichwald J, Danner S, Staab D, Capetillo-Zarate E, Yamaguchi H, Saido TC, Wiederhold KH, Thal DR, Staufenbiel M. Abramowski D, et al. Among authors: staufenbiel m. J Neurosci. 2012 Jan 25;32(4):1273-83. doi: 10.1523/JNEUROSCI.4586-11.2012. J Neurosci. 2012. PMID: 22279212 Free PMC article.
Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.
Rijal Upadhaya A, Capetillo-Zarate E, Kosterin I, Abramowski D, Kumar S, Yamaguchi H, Walter J, Fändrich M, Staufenbiel M, Thal DR. Rijal Upadhaya A, et al. Among authors: staufenbiel m. Neurobiol Aging. 2012 Nov;33(11):2641-60. doi: 10.1016/j.neurobiolaging.2011.12.032. Epub 2012 Feb 2. Neurobiol Aging. 2012. PMID: 22305478
Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice.
Balakrishnan K, Rijal Upadhaya A, Steinmetz J, Reichwald J, Abramowski D, Fändrich M, Kumar S, Yamaguchi H, Walter J, Staufenbiel M, Thal DR. Balakrishnan K, et al. Among authors: staufenbiel m. Acta Neuropathol Commun. 2015 Jul 4;3:41. doi: 10.1186/s40478-015-0217-z. Acta Neuropathol Commun. 2015. PMID: 26141728 Free PMC article.
Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.
Capetillo-Zarate E, Staufenbiel M, Abramowski D, Haass C, Escher A, Stadelmann C, Yamaguchi H, Wiestler OD, Thal DR. Capetillo-Zarate E, et al. Among authors: staufenbiel m. Brain. 2006 Nov;129(Pt 11):2992-3005. doi: 10.1093/brain/awl176. Epub 2006 Jul 14. Brain. 2006. PMID: 16844716
The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice.
Rijal Upadhaya A, Scheibe F, Kosterin I, Abramowski D, Gerth J, Kumar S, Liebau S, Yamaguchi H, Walter J, Staufenbiel M, Thal DR. Rijal Upadhaya A, et al. Among authors: staufenbiel m. Acta Neuropathol Commun. 2013 Nov 18;1(1):77. doi: 10.1186/2051-5960-1-77. Acta Neuropathol Commun. 2013. PMID: 24252227 Free PMC article.
Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice.
Thal DR, Larionov S, Abramowski D, Wiederhold KH, Van Dooren T, Yamaguchi H, Haass C, Van Leuven F, Staufenbiel M, Capetillo-Zarate E. Thal DR, et al. Among authors: staufenbiel m. Neurobiol Aging. 2007 Aug;28(8):1221-30. doi: 10.1016/j.neurobiolaging.2006.05.029. Epub 2006 Jul 3. Neurobiol Aging. 2007. PMID: 16815595
215 results