Xu Z - Search Results

1

IMPA1-derived inositol maintains stemness in castration-resistant prostate cancer via IMPDH2 activation.

Hsu CC, Wang G, Li CF, Zhang X, Cai Z, Chen T, Pan BS, Manne RK, Deep G, Gu H, Wang Y, Peng D, Penugurti V, Zhou X, Xu Z, Chen Z, Chen M, Armstrong AJ, Huang J, Li HY, Lin HK. Hsu CC, et al. Among authors: xu z. J Exp Med. 2024 Nov 4;221(11):e20231832. doi: 10.1084/jem.20231832. Epub 2024 Oct 29. J Exp Med. 2024. PMID: 39470689

2

Identification of pyrazine-based TrkA inhibitors: design, synthesis, evaluation, and computational modeling studies.

Frett B, McConnell N, Wang Y, Xu Z, Ambrose A, Li HY. Frett B, et al. Among authors: xu z. Medchemcomm. 2014 Oct 1;5(10):1507-1514. doi: 10.1039/C4MD00251B. Epub 2014 Aug 11. Medchemcomm. 2014. PMID: 26843921 Free PMC article.

3

Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation.

Lei J, Xu ZG, Li SQ, Xu J, Zhu J, Chen ZZ. Lei J, et al. Mol Divers. 2016 Nov;20(4):859-865. doi: 10.1007/s11030-016-9679-6. Epub 2016 Jun 7. Mol Divers. 2016. PMID: 27272954

4

Efficient Synthesis of Fused Oxazepino-isoquinoline Scaffolds via an Ugi, Followed by an Intramolecular Cyclization.

Li Y, Meng JP, Lei J, Chen ZZ, Tang DY, Zhu J, Zhang J, Xu ZG. Li Y, et al. ACS Comb Sci. 2017 May 8;19(5):324-330. doi: 10.1021/acscombsci.7b00002. Epub 2017 Mar 16. ACS Comb Sci. 2017. PMID: 28271876

5

Recent advances in the development of polycyclic skeletons via Ugi reaction cascades.

Lei J, Meng JP, Tang DY, Frett B, Chen ZZ, Xu ZG. Lei J, et al. Mol Divers. 2018 May;22(2):503-516. doi: 10.1007/s11030-017-9811-2. Epub 2018 Jan 16. Mol Divers. 2018. PMID: 29340996 Review.

6

Acid-Promoted One-Pot Synthesis of Substituted Furan and 6-Methylpyrazin-2(1 H)-one Derivatives via Allene Intermediate Formed in Situ.

Lei J, Xu ZG, Tang DY, Li Y, Xu J, Li HY, Zhu J, Chen ZZ. Lei J, et al. ACS Comb Sci. 2018 May 14;20(5):292-297. doi: 10.1021/acscombsci.8b00005. Epub 2018 Apr 11. ACS Comb Sci. 2018. PMID: 29620860

7

Functionalized Spiroindolines with Anticancer Activity through a Metal-Free Post-Ugi Diastereoselective One-Pot Cascade Reaction.

Xu ZG, Li SQ, Meng JP, Tang DY, He LJ, Lei J, Lin HK, Li HY, Chen ZZ. Xu ZG, et al. Chemistry. 2018 May 7;24(26):6732-6736. doi: 10.1002/chem.201801081. Epub 2018 Apr 20. Chemistry. 2018. PMID: 29676029 Free PMC article.

8

Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.

He LJ, Yang DL, Li SQ, Zhang YJ, Tang Y, Lei J, Frett B, Lin HK, Li HY, Chen ZZ, Xu ZG. He LJ, et al. Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908. doi: 10.1016/j.bmc.2018.06.010. Epub 2018 Jun 12. Bioorg Med Chem. 2018. PMID: 29921474 Free PMC article.

9

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways.

Zhang YJ, Xu ZG, Li SQ, He LJ, Tang Y, Chen ZZ, Yang DL. Zhang YJ, et al. Cancer Cell Int. 2018 Jun 28;18:90. doi: 10.1186/s12935-018-0588-x. eCollection 2018. Cancer Cell Int. 2018. PMID: 29988358 Free PMC article.

10

Synthesis of Constrained Heterocycles Employing Two Post-Ugi Cyclization Methods for Rapid Library Generation with In Cellulo Activity.

McConnell N, Xu Z, Kumarasamy V, Sun D, Frett B, Li HY. McConnell N, et al. Among authors: xu z. ChemistrySelect. 2017 Dec 11;2(35):11821-11825. doi: 10.1002/slct.201702179. Epub 2017 Dec 19. ChemistrySelect. 2017. PMID: 30140731 Free PMC article.

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