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Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer.
Saito Y, Xiao Y, Yao J, Li Y, Liu W, Yuzhalin AE, Shyu YM, Li H, Yuan X, Li P, Zhang Q, Li Z, Wei Y, Yin X, Zhao J, Kariminia SM, Wu YC, Wang J, Yang J, Xia W, Sun Y, Jho EH, Chiao PJ, Hwang RF, Ying H, Wang H, Zhao Z, Maitra A, Hung MC, DePinho RA, Yu D. Saito Y, et al. Among authors: sun y. Cell Discov. 2024 Oct 29;10(1):109. doi: 10.1038/s41421-024-00720-w. Cell Discov. 2024. PMID: 39468013 Free PMC article.
Powering Tumor Metastasis with Recycled Fuel.
Hung MC, Yang R, Sun Y. Hung MC, et al. Among authors: sun y. Cancer Cell. 2016 Sep 12;30(3):374-375. doi: 10.1016/j.ccell.2016.08.014. Cancer Cell. 2016. PMID: 27622330 Free article.
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition.
Yuzhalin AE, Lowery FJ, Saito Y, Yuan X, Yao J, Duan Y, Ding J, Acharya S, Zhang C, Fajardo A, Chen HN, Wei Y, Sun Y, Zhang L, Xiao Y, Li P, Lorenzi PL, Huse JT, Fan H, Zhao Z, Hung MC, Yu D. Yuzhalin AE, et al. Among authors: sun y. Nat Cell Biol. 2024 Oct;26(10):1773-1789. doi: 10.1038/s41556-024-01509-5. Epub 2024 Sep 20. Nat Cell Biol. 2024. PMID: 39304713
Deubiquitylation and stabilization of PTEN by USP13.
Zhang J, Zhang P, Wei Y, Piao HL, Wang W, Maddika S, Wang M, Chen D, Sun Y, Hung MC, Chen J, Ma L. Zhang J, et al. Among authors: sun y. Nat Cell Biol. 2013 Dec;15(12):1486-1494. doi: 10.1038/ncb2874. Epub 2013 Nov 24. Nat Cell Biol. 2013. PMID: 24270891 Free PMC article.
ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.
Zhang P, Xiao Z, Wang S, Zhang M, Wei Y, Hang Q, Kim J, Yao F, Rodriguez-Aguayo C, Ton BN, Lee M, Wang Y, Zhou Z, Zeng L, Hu X, Lawhon SE, Siverly AN, Su X, Li J, Xie X, Cheng X, Liu LC, Chang HW, Chiang SF, Lopez-Berestein G, Sood AK, Chen J, You MJ, Sun SC, Liang H, Huang Y, Yang X, Sun D, Sun Y, Hung MC, Ma L. Zhang P, et al. Among authors: sun sc, sun d, sun y. Cell Rep. 2018 Apr 17;23(3):823-837. doi: 10.1016/j.celrep.2018.03.078. Cell Rep. 2018. PMID: 29669287 Free PMC article.
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