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The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species.
Channels (Austin). 2024 Dec;18(1):2420651. doi: 10.1080/19336950.2024.2420651. Epub 2024 Oct 27.
Channels (Austin). 2024.
PMID: 39462453
Free PMC article.
Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart.
De la Cruz A, Wu X, Rainer QC, Hiniesto-Iñigo I, Perez ME, Edler I, Liin SI, Larsson HP.
De la Cruz A, et al. Among authors: hiniesto inigo i.
Int J Mol Sci. 2023 Jul 28;24(15):12092. doi: 10.3390/ijms241512092.
Int J Mol Sci. 2023.
PMID: 37569465
Free PMC article.
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Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval.
Hiniesto-Iñigo I, Castro-Gonzalez LM, Corradi V, Skarsfeldt MA, Yazdi S, Lundholm S, Nikesjö J, Noskov SY, Bentzen BH, Tieleman DP, Liin SI.
Hiniesto-Iñigo I, et al.
EBioMedicine. 2023 Mar;89:104459. doi: 10.1016/j.ebiom.2023.104459. Epub 2023 Feb 14.
EBioMedicine. 2023.
PMID: 36796231
Free PMC article.
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