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The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi.
Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser L, Liedl KR, Schmidt O, Teis D. Weyer Y, et al. Among authors: liedl kr. Nat Commun. 2024 Oct 26;15(1):9257. doi: 10.1038/s41467-024-53676-6. Nat Commun. 2024. PMID: 39461958 Free PMC article.
Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.
Weiss AKH, Naschberger A, Loeffler JR, Gstach H, Bowler MW, Holzknecht M, Cappuccio E, Pittl A, Etemad S, Dunzendorfer-Matt T, Scheffzek K, Liedl KR, Jansen-Dürr P. Weiss AKH, et al. Among authors: liedl kr. Biochem J. 2018 Nov 20;475(22):3561-3576. doi: 10.1042/BCJ20180750. Biochem J. 2018. PMID: 30348641 Free PMC article.
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: liedl kr. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
269 results