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Page 1
Validation and clinical performance of a single test, DNA based endometrial cancer molecular classifier.
Jamieson A, Grube M, Kommoss F, Lum A, Leung S, Chiu D, Henderson G, Heitz F, Heublein S, Zeimet AG, Hasenburg A, Diebold J, Walter C, Staebler A, Reynolds J, Lapuk A, McConechy MK, Huntsman DG, Gilks B, Kommoss S, McAlpine JN. Jamieson A, et al. Among authors: lapuk a. Int J Gynecol Cancer. 2024 Dec 2;34(12):1888-1897. doi: 10.1136/ijgc-2024-005916. Int J Gynecol Cancer. 2024. PMID: 39461743
Prevalence of the EGFR T790M and other resistance mutations in the Australian population and histopathological correlation in a small subset of cases.
Kim RH, Lapuk A, Harraway J, Lee E, Walsh M, Topkas E, Jones V, Burn J, Baillie T, Lim C, Nejad K, Muljono A, Gagne E, McConechy MK, Zein Y, Maclean F, Gill AJ, Vargas AC. Kim RH, et al. Among authors: lapuk a. Pathology. 2020 Jun;52(4):410-420. doi: 10.1016/j.pathol.2020.03.003. Epub 2020 Apr 28. Pathology. 2020. PMID: 32359774
The Proteogenomic Landscape of Curable Prostate Cancer.
Sinha A, Huang V, Livingstone J, Wang J, Fox NS, Kurganovs N, Ignatchenko V, Fritsch K, Donmez N, Heisler LE, Shiah YJ, Yao CQ, Alfaro JA, Volik S, Lapuk A, Fraser M, Kron K, Murison A, Lupien M, Sahinalp C, Collins CC, Tetu B, Masoomian M, Berman DM, van der Kwast T, Bristow RG, Kislinger T, Boutros PC. Sinha A, et al. Among authors: lapuk a. Cancer Cell. 2019 Mar 18;35(3):414-427.e6. doi: 10.1016/j.ccell.2019.02.005. Cancer Cell. 2019. PMID: 30889379 Free PMC article.
Widespread and Functional RNA Circularization in Localized Prostate Cancer.
Chen S, Huang V, Xu X, Livingstone J, Soares F, Jeon J, Zeng Y, Hua JT, Petricca J, Guo H, Wang M, Yousif F, Zhang Y, Donmez N, Ahmed M, Volik S, Lapuk A, Chua MLK, Heisler LE, Foucal A, Fox NS, Fraser M, Bhandari V, Shiah YJ, Guan J, Li J, Orain M, Picard V, Hovington H, Bergeron A, Lacombe L, Fradet Y, Têtu B, Liu S, Feng F, Wu X, Shao YW, Komor MA, Sahinalp C, Collins C, Hoogstrate Y, de Jong M, Fijneman RJA, Fei T, Jenster G, van der Kwast T, Bristow RG, Boutros PC, He HH. Chen S, et al. Among authors: lapuk a. Cell. 2019 Feb 7;176(4):831-843.e22. doi: 10.1016/j.cell.2019.01.025. Cell. 2019. PMID: 30735634 Free article.
Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Prentice LM, Miller RR, Knaggs J, Mazloomian A, Aguirre Hernandez R, Franchini P, Parsa K, Tessier-Cloutier B, Lapuk A, Huntsman D, Schaeffer DF, Sheffield BS. Prentice LM, et al. Among authors: lapuk a. PLoS One. 2018 Apr 26;13(4):e0196434. doi: 10.1371/journal.pone.0196434. eCollection 2018. PLoS One. 2018. PMID: 29698444 Free PMC article.
Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer.
Wyatt AW, Mo F, Wang K, McConeghy B, Brahmbhatt S, Jong L, Mitchell DM, Johnston RL, Haegert A, Li E, Liew J, Yeung J, Shrestha R, Lapuk AV, McPherson A, Shukin R, Bell RH, Anderson S, Bishop J, Hurtado-Coll A, Xiao H, Chinnaiyan AM, Mehra R, Lin D, Wang Y, Fazli L, Gleave ME, Volik SV, Collins CC. Wyatt AW, et al. Among authors: lapuk av. Genome Biol. 2014 Aug 26;15(8):426. doi: 10.1186/s13059-014-0426-y. Genome Biol. 2014. PMID: 25155515 Free PMC article.
The role of mRNA splicing in prostate cancer.
Lapuk AV, Volik SV, Wang Y, Collins CC. Lapuk AV, et al. Asian J Androl. 2014 Jul-Aug;16(4):515-21. doi: 10.4103/1008-682X.127825. Asian J Androl. 2014. PMID: 24830689 Free PMC article. Review.
Poly-gene fusion transcripts and chromothripsis in prostate cancer.
Wu C, Wyatt AW, McPherson A, Lin D, McConeghy BJ, Mo F, Shukin R, Lapuk AV, Jones SJ, Zhao Y, Marra MA, Gleave ME, Volik SV, Wang Y, Sahinalp SC, Collins CC. Wu C, et al. Among authors: lapuk av. Genes Chromosomes Cancer. 2012 Dec;51(12):1144-53. doi: 10.1002/gcc.21999. Epub 2012 Aug 25. Genes Chromosomes Cancer. 2012. PMID: 22927308
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer.
Lapuk AV, Wu C, Wyatt AW, McPherson A, McConeghy BJ, Brahmbhatt S, Mo F, Zoubeidi A, Anderson S, Bell RH, Haegert A, Shukin R, Wang Y, Fazli L, Hurtado-Coll A, Jones EC, Hach F, Hormozdiari F, Hajirasouliha I, Boutros PC, Bristow RG, Zhao Y, Marra MA, Fanjul A, Maher CA, Chinnaiyan AM, Rubin MA, Beltran H, Sahinalp SC, Gleave ME, Volik SV, Collins CC. Lapuk AV, et al. J Pathol. 2012 Jul;227(3):286-97. doi: 10.1002/path.4047. J Pathol. 2012. PMID: 22553170 Free PMC article.
30 results