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A phase 2a trial of brepocitinib for cicatricial alopecia.
David E, Shokrian N, Del Duca E, Meariman M, Dubin C, Hawkins K, Andrews E, Sikand S, Singer G, Oemar B, Estrada Y, Bose S, Pulsinelli J, Mahling P, Da Rosa JC, Ungar B, Peeva E, Guttman-Yassky E. David E, et al. Among authors: bose s. J Am Acad Dermatol. 2024 Oct 24:S0190-9622(24)03043-3. doi: 10.1016/j.jaad.2024.09.073. Online ahead of print. J Am Acad Dermatol. 2024. PMID: 39461505 Free article.
Age of onset defines two distinct profiles of atopic dermatitis in adults.
Facheris P, Da Rosa JC, Pagan AD, Angelov M, Del Duca E, Rabinowitz G, Gómez-Arias PJ, Rothenberg-Lausell C, Estrada YD, Bose S, Chowdhury M, Shemer A, Pavel AB, Guttman-Yassky E. Facheris P, et al. Among authors: bose s. Allergy. 2023 Aug;78(8):2202-2214. doi: 10.1111/all.15741. Epub 2023 Apr 18. Allergy. 2023. PMID: 37032461
Oral difelikefalin reduces moderate to severe pruritus and expression of pruritic and inflammatory biomarkers in subjects with atopic dermatitis.
Guttman-Yassky E, Facheris P, Da Rosa JC, Rothenberg-Lausell C, Del Duca E, David E, Estrada Y, Liu Y, Bose S, Chowdhury M, Munera C, Goncalves J, Nograles K, Kim BS, Lebwohl M. Guttman-Yassky E, et al. Among authors: bose s. J Allergy Clin Immunol. 2023 Oct;152(4):916-926. doi: 10.1016/j.jaci.2023.06.023. Epub 2023 Jul 13. J Allergy Clin Immunol. 2023. PMID: 37453614 Free article.
Alopecia areata exhibits cutaneous and systemic OX40 activation across atopic backgrounds.
Kim M, Del Duca E, Dahabreh D, Lozano-Ojalvo D, Carroll B, Manson M, Bose S, Gour D, NandyMazumdar M, Liu Y, Yu Ekey M, Chowdhury A, Angelov M, Ungar B, Estrada Y, Guttman-Yassky E. Kim M, et al. Among authors: bose s. Allergy. 2024 Dec;79(12):3401-3414. doi: 10.1111/all.16268. Epub 2024 Aug 8. Allergy. 2024. PMID: 39115359
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.
Beckmann ND, Comella PH, Cheng E, Lepow L, Beckmann AG, Tyler SR, Mouskas K, Simons NW, Hoffman GE, Francoeur NJ, Del Valle DM, Kang G, Do A, Moya E, Wilkins L, Le Berichel J, Chang C, Marvin R, Calorossi S, Lansky A, Walker L, Yi N, Yu A, Chung J, Hartnett M, Eaton M, Hatem S, Jamal H, Akyatan A, Tabachnikova A, Liharska LE, Cotter L, Fennessy B, Vaid A, Barturen G, Shah H, Wang YC, Sridhar SH, Soto J, Bose S, Madrid K, Ellis E, Merzier E, Vlachos K, Fishman N, Tin M, Smith M, Xie H, Patel M, Nie K, Argueta K, Harris J, Karekar N, Batchelor C, Lacunza J, Yishak M, Tuballes K, Scott I, Kumar A, Jaladanki S, Agashe C, Thompson R, Clark E, Losic B, Peters L; Mount Sinai COVID-19 Biobank Team; Roussos P, Zhu J, Wang W, Kasarskis A, Glicksberg BS, Nadkarni G, Bogunovic D, Elaiho C, Gangadharan S, Ofori-Amanfo G, Alesso-Carra K, Onel K, Wilson KM, Argmann C, Bunyavanich S, Alarcón-Riquelme ME, Marron TU, Rahman A, Kim-Schulze S, Gnjatic S, Gelb BD, Merad M, Sebra R, Schadt EE, Charney AW. Beckmann ND, et al. Among authors: bose s. Nat Commun. 2021 Aug 11;12(1):4854. doi: 10.1038/s41467-021-24981-1. Nat Commun. 2021. PMID: 34381049 Free PMC article.
Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children.
Beckmann ND, Comella PH, Cheng E, Lepow L, Beckmann AG, Mouskas K, Simons NW, Hoffman GE, Francoeur NJ, Del Valle DM, Kang G, Moya E, Wilkins L, Le Berichel J, Chang C, Marvin R, Calorossi S, Lansky A, Walker L, Yi N, Yu A, Hartnett M, Eaton M, Hatem S, Jamal H, Akyatan A, Tabachnikova A, Liharska LE, Cotter L, Fennessey B, Vaid A, Barturen G, Tyler SR, Shah H, Wang YC, Sridhar SH, Soto J, Bose S, Madrid K, Ellis E, Merzier E, Vlachos K, Fishman N, Tin M, Smith M, Xie H, Patel M, Argueta K, Harris J, Karekar N, Batchelor C, Lacunza J, Yishak M, Tuballes K, Scott L, Kumar A, Jaladanki S, Thompson R, Clark E, Losic B; Mount Sinai COVID-19 Biobank Team; Zhu J, Wang W, Kasarskis A, Glicksberg BS, Nadkarni G, Bogunovic D, Elaiho C, Gangadharan S, Ofori-Amanfo G, Alesso-Carra K, Onel K, Wilson KM, Argmann C, Alarcón-Riquelme ME, Marron TU, Rahman A, Kim-Schulze S, Gnjatic S, Gelb BD, Merad M, Sebra R, Schadt EE, Charney AW. Beckmann ND, et al. Among authors: bose s. medRxiv [Preprint]. 2020 Sep 2:2020.08.29.20182899. doi: 10.1101/2020.08.29.20182899. medRxiv. 2020. Update in: Nat Commun. 2021 Aug 11;12(1):4854. doi: 10.1038/s41467-021-24981-1 PMID: 32909006 Free PMC article. Updated. Preprint.
2,517 results