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High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity.
Lee S, Weiss T, Bühler M, Mena J, Lottenbach Z, Wegmann R, Sun M, Bihl M, Augustynek B, Baumann SP, Goetze S, van Drogen A, Pedrioli PGA, Penton D, Festl Y, Buck A, Kirschenbaum D, Zeitlberger AM, Neidert MC, Vasella F, Rushing EJ, Wollscheid B, Hediger MA, Weller M, Snijder B. Lee S, et al. Among authors: penton d. Nat Med. 2024 Nov;30(11):3196-3208. doi: 10.1038/s41591-024-03224-y. Epub 2024 Sep 20. Nat Med. 2024. PMID: 39304781 Free PMC article.
Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis.
Banki E, Fisi V, Moser S, Wengi A, Carrel M, Loffing-Cueni D, Penton D, Kratschmar DV, Rizzo L, Lienkamp S, Odermatt A, Rinschen MM, Loffing J. Banki E, et al. Among authors: penton d. Kidney Int. 2021 Oct;100(4):850-869. doi: 10.1016/j.kint.2021.06.030. Epub 2021 Jul 10. Kidney Int. 2021. PMID: 34252449 Free article.
32 results