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Page 1
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma.
Shu DH, Ho WJ, Kagohara LT, Girgis A, Shin SM, Danilova L, Lee JW, Sidiropoulos DN, Mitchell S, Munjal K, Howe K, Bendinelli KJ, Kartalia E, Qi H, Mo G, Montagne J, Leatherman JM, Lopez-Vidal TY, Zhu Q, Huff AL, Yuan X, Hernandez A, Coyne EM, Zaidi N, Zabransky DJ, Engle LL, Ogurtsova A, Baretti M, Laheru D, Durham JN, Wang H, Sunshine JC, Johnston RJ, Deutsch JS, Taube JM, Anders RA, Jaffee EM, Fertig EJ, Yarchoan M. Shu DH, et al. Among authors: yuan x. Nat Immunol. 2024 Nov;25(11):2110-2123. doi: 10.1038/s41590-024-01992-w. Epub 2024 Oct 25. Nat Immunol. 2024. PMID: 39455893
Profiling of syngeneic mouse HCC tumor models as a framework to understand anti-PD-1 sensitive tumor microenvironments.
Zabransky DJ, Danilova L, Leatherman JM, Lopez-Vidal TY, Sanchez J, Charmsaz S, Gross NE, Shin S, Yuan X, Hernandez A, Yang H, Xavier S, Shu D, Saeed A, Munjal K, Kamdar Z, Kagohara LT, Jaffee EM, Yarchoan M, Ho WJ. Zabransky DJ, et al. Among authors: yuan x. Hepatology. 2023 May 1;77(5):1566-1579. doi: 10.1002/hep.32707. Epub 2023 Apr 17. Hepatology. 2023. PMID: 35941803 Free PMC article.
Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade.
Shu DH, Ho WJ, Kagohara LT, Girgis A, Shin SM, Danilova L, Lee JW, Sidiropoulos DN, Mitchell S, Munjal K, Howe K, Bendinelli KJ, Qi H, Mo G, Montagne J, Leatherman JM, Lopez-Vidal TY, Zhu Q, Huff AL, Yuan X, Hernandez A, Coyne EM, Zaidi N, Zabransky DJ, Engle LL, Ogurtsova A, Baretti M, Laheru D, Durham JN, Wang H, Anders R, Jaffee EM, Fertig EJ, Yarchoan M. Shu DH, et al. Among authors: yuan x. bioRxiv [Preprint]. 2023 Oct 26:2023.10.16.562104. doi: 10.1101/2023.10.16.562104. bioRxiv. 2023. PMID: 37904980 Free PMC article. Preprint.
CyTOF protocol for immune monitoring of solid tumors from mouse models.
Shin SM, Hernandez A, Coyne E, Munjal K, Gross NE, Charmsaz S, Yuan X, Yang H, Ho WJ. Shin SM, et al. Among authors: yuan x. STAR Protoc. 2023 Mar 17;4(1):101949. doi: 10.1016/j.xpro.2022.101949. Epub 2022 Dec 19. STAR Protoc. 2023. PMID: 36538397 Free PMC article.
Phosphodiesterase-5 inhibition collaborates with vaccine-based immunotherapy to reprogram myeloid cells in pancreatic ductal adenocarcinoma.
Gross NE, Zhang Z, Mitchell JT, Charmsaz S, Hernandez AG, Coyne EM, Shin SM, Vargas Carvajal DC, Sidiropoulos DN, Cho Y, Mo G, Yuan X, Cannon C, Suresh Babu J, Lyman MR, Armstrong T, Kagohara LT, Bever KM, Le DT, Jaffee EM, Fertig EJ, Ho WJ. Gross NE, et al. Among authors: yuan x. JCI Insight. 2024 Aug 6;9(18):e179292. doi: 10.1172/jci.insight.179292. JCI Insight. 2024. PMID: 39106104 Free PMC article.
Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders.
Sidiropoulos DN, Shin SM, Wetzel M, Girgis AA, Bergman D, Danilova L, Perikala S, Shu DH, Montagne JM, Deshpande A, Leatherman J, Dequiedt L, Jacobs V, Ogurtsova A, Mo G, Yuan X, Lvovs D, Stein-O'Brien G, Yarchoan M, Zhu Q, Harper EI, Weeraratna AT, Kiemen AL, Jaffee EM, Zheng L, Ho WJ, Anders RA, Fertig EJ, Kagohara LT. Sidiropoulos DN, et al. Among authors: yuan x. bioRxiv [Preprint]. 2024 Sep 23:2024.09.22.613714. doi: 10.1101/2024.09.22.613714. bioRxiv. 2024. PMID: 39386736 Free PMC article. Preprint.
Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors.
Ludford K, Ho WJ, Thomas JV, Raghav KPS, Murphy MB, Fleming ND, Lee MS, Smaglo BG, You YN, Tillman MM, Kamiya-Matsuoka C, Thirumurthi S, Messick C, Johnson B, Vilar E, Dasari A, Shin S, Hernandez A, Yuan X, Yang H, Foo WC, Qiao W, Maru D, Kopetz S, Overman MJ. Ludford K, et al. Among authors: yuan x. J Clin Oncol. 2023 Apr 20;41(12):2181-2190. doi: 10.1200/JCO.22.01351. Epub 2023 Jan 9. J Clin Oncol. 2023. PMID: 36623241 Free PMC article. Clinical Trial.
Ex vivo assays to detect complement activation in complementopathies.
Yuan X, Yu J, Gerber G, Chaturvedi S, Cole M, Chen H, Metjian A, Sperati CJ, Braunstein EM, Brodsky RA. Yuan X, et al. Clin Immunol. 2020 Dec;221:108616. doi: 10.1016/j.clim.2020.108616. Epub 2020 Oct 24. Clin Immunol. 2020. PMID: 33148511 Free PMC article.
Complement dysregulation is associated with severe COVID-19 illness.
Yu J, Gerber GF, Chen H, Yuan X, Chaturvedi S, Braunstein EM, Brodsky RA. Yu J, et al. Among authors: yuan x. Haematologica. 2022 May 1;107(5):1095-1105. doi: 10.3324/haematol.2021.279155. Haematologica. 2022. PMID: 34289657 Free PMC article.
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