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Page 1
Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.
de Almagro MC, Goncharov T, Izrael-Tomasevic A, Duttler S, Kist M, Varfolomeev E, Wu X, Lee WP, Murray J, Webster JD, Yu K, Kirkpatrick DS, Newton K, Vucic D. de Almagro MC, et al. Among authors: goncharov t. Cell Death Differ. 2017 Jan;24(1):26-37. doi: 10.1038/cdd.2016.78. Epub 2016 Aug 12. Cell Death Differ. 2017. PMID: 27518435 Free PMC article.
Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury.
Stark K, Goncharov T, Varfolomeev E, Xie L, Ngu H, Peng I, Anderson KR, Verschueren E, Choi M, Kirkpatrick DS, Easton A, Webster JD, McKenzie BS, Vucic D, Bingol B. Stark K, et al. Among authors: goncharov t. Cell Death Dis. 2021 Apr 7;12(4):379. doi: 10.1038/s41419-021-03651-6. Cell Death Dis. 2021. PMID: 33828080 Free PMC article.
XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death.
Witt A, Goncharov T, Lee YM, Kist M, Dohse M, Eastham J, Dugger D, Newton K, Webster JD, Vucic D. Witt A, et al. Among authors: goncharov t. Cell Death Dis. 2023 Apr 11;14(4):262. doi: 10.1038/s41419-023-05793-1. Cell Death Dis. 2023. PMID: 37041175 Free PMC article.
Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Zhang J, Webster JD, Dugger DL, Goncharov T, Roose-Girma M, Hung J, Kwon YC, Vucic D, Newton K, Dixit VM. Zhang J, et al. Among authors: goncharov t. Cell Rep. 2019 May 28;27(9):2679-2689.e3. doi: 10.1016/j.celrep.2019.04.111. Cell Rep. 2019. PMID: 31141691 Free article.
RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Webster JD, Kwon YC, Park S, Zhang H, Corr N, Ljumanovic N, Adedeji AO, Varfolomeev E, Goncharov T, Preston J, Santagostino SF, Patel S, Xu M, Maher J, McKenzie BS, Vucic D. Webster JD, et al. Among authors: goncharov t. J Leukoc Biol. 2020 Jun;107(6):941-952. doi: 10.1002/JLB.3MA1219-398R. Epub 2020 Jan 27. J Leukoc Biol. 2020. PMID: 31985117 Free PMC article.
Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
Prado-Acosta M, Jeong S, Utrero-Rico A, Goncharov T, Webster JD, Holler E, Morales G, Dellepiane S, Levine JE, Rothenberg ME, Vucic D, Ferrara JLM. Prado-Acosta M, et al. Among authors: goncharov t. Sci Transl Med. 2023 Dec 20;15(727):eadf8366. doi: 10.1126/scitranslmed.adf8366. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117900 Free PMC article.
31 results