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Page 1
Molecular mechanism of ligand gating and opening of NMDA receptor.
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H. Chou TH, et al. Among authors: fritzemeier rg. Nature. 2024 Aug;632(8023):209-217. doi: 10.1038/s41586-024-07742-0. Epub 2024 Jul 31. Nature. 2024. PMID: 39085540 Free PMC article.
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
D'Erasmo MP, Akins NS, Ma P, Jing Y, Swanger SA, Sharma SK, Bartsch PW, Menaldino DS, Arcoria PJ, Bui TT, Pons-Bennaceur A, Le P, Allen JP, Ullman EZ, Nocilla KA, Zhang J, Perszyk RE, Kim S, Acker TM, Taz A, Burton SL, Coe K, Fritzemeier RG, Burnashev N, Yuan H, Liotta DC, Traynelis SF. D'Erasmo MP, et al. Among authors: fritzemeier rg. ACS Chem Neurosci. 2023 Sep 6;14(17):3059-3076. doi: 10.1021/acschemneuro.3c00181. Epub 2023 Aug 11. ACS Chem Neurosci. 2023. PMID: 37566734 Free PMC article.
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.
Tanaka S, Zheng S, Kharel Y, Fritzemeier RG, Huang T, Foster D, Poudel N, Goggins E, Yamaoka Y, Rudnicka KP, Lipsey JE, Radel HV, Ryuh SM, Inoue T, Yao J, Rosin DL, Schwab SR, Santos WL, Lynch KR, Okusa MD. Tanaka S, et al. Among authors: fritzemeier rg. Sci Transl Med. 2022 Aug 17;14(658):eabj2681. doi: 10.1126/scitranslmed.abj2681. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976996 Free PMC article.
Organocatalytic trans Phosphinoboration of Internal Alkynes.
Fritzemeier RG, Nekvinda J, Vogels CM, Rosenblum CA, Slebodnick C, Westcott SA, Santos WL. Fritzemeier RG, et al. Angew Chem Int Ed Engl. 2020 Aug 17;59(34):14358-14362. doi: 10.1002/anie.202006096. Epub 2020 Jul 1. Angew Chem Int Ed Engl. 2020. PMID: 32406101
Route to Air and Moisture Stable β-Difluoroboryl Acrylamides.
Fritzemeier RG, Medici EJ, Szwetkowski C, Wonilowicz LG, Sibley CD, Slebodnick C, Santos WL. Fritzemeier RG, et al. Org Lett. 2019 Oct 4;21(19):8053-8057. doi: 10.1021/acs.orglett.9b03031. Epub 2019 Sep 20. Org Lett. 2019. PMID: 31538791