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Page 1
Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response.
Rahman MA, Bissa M, Scinto H, Howe SE, Sarkis S, Ma ZM, Gutowska A, Jiang X, Luo CC, Schifanella L, Moles R, Silva de Castro I, Basu S, N'guessan KF, Williams LD, Becerra-Flores M, Doster MN, Hoang T, Choo-Wosoba H, Woode E, Sui Y, Tomaras GD, Paquin-Proulx D, Rao M, Talton JD, Kong XP, Zolla-Pazner S, Cardozo T, Franchini G, Berzofsky JA. Rahman MA, et al. Among authors: doster mn. Nat Commun. 2024 Oct 22;15(1):9102. doi: 10.1038/s41467-024-53359-2. Nat Commun. 2024. PMID: 39438480 Free PMC article.
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition.
Vaccari M, Fourati S, Gordon SN, Brown DR, Bissa M, Schifanella L, Silva de Castro I, Doster MN, Galli V, Omsland M, Fujikawa D, Gorini G, Liyanage NPM, Trinh HV, McKinnon KM, Foulds KE, Keele BF, Roederer M, Koup RA, Shen X, Tomaras GD, Wong MP, Munoz KJ, Gach JS, Forthal DN, Montefiori DC, Venzon DJ, Felber BK, Rosati M, Pavlakis GN, Rao M, Sekaly RP, Franchini G. Vaccari M, et al. Among authors: doster mn. Nat Med. 2018 Jun;24(6):847-856. doi: 10.1038/s41591-018-0025-7. Epub 2018 May 21. Nat Med. 2018. PMID: 29785023 Free PMC article.
Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate.
Vaccari M, Fourati S, Brown DR, Silva de Castro I, Bissa M, Schifanella L, Doster MN, Foulds KE, Roederer M, Koup RA, Sui Y, Berzofsky JA, Sekaly RP, Franchini G. Vaccari M, et al. Among authors: doster mn. Front Immunol. 2019 May 14;10:1072. doi: 10.3389/fimmu.2019.01072. eCollection 2019. Front Immunol. 2019. PMID: 31139193 Free PMC article.
ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.
Schifanella L, Barnett SW, Bissa M, Galli V, Doster MN, Vaccari M, Tomaras GD, Shen X, Phogat S, Pal R, Montefiori DC, LaBranche CC, Rao M, Trinh HV, Washington-Parks R, Liyanage NPM, Gorini G, Brown DR, Liang F, Loré K, Venzon DJ, Magnanelli W, Metrinko M, Kramer J, Breed M, Alter G, Ruprecht RM, Franchini G. Schifanella L, et al. Among authors: doster mn. PLoS Pathog. 2019 Dec 3;15(12):e1008121. doi: 10.1371/journal.ppat.1008121. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31794588 Free PMC article.
HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC.
Bissa M, Kim S, Galli V, Fourati S, Sarkis S, Arakelyan A, de Castro IS, Rahman MA, Fujiwara S, Vaccari M, Tomalka JA, Stamos JD, Schifanella L, Gorini G, Moles R, Gutowska A, Ferrari G, Lobanov A, Montefiori DC, Nelson GW, Cam MC, Chakhtoura M, Haddad EK, Doster MN, McKinnon K, Brown S, Venzon DJ, Choo-Wosoba H, Breed MW, Killoran KE, Kramer J, Margolis L, Sekaly RP, Hager GL, Franchini G. Bissa M, et al. Among authors: doster mn. Nat Commun. 2023 Feb 2;14(1):575. doi: 10.1038/s41467-023-36109-8. Nat Commun. 2023. PMID: 36732510 Free PMC article.
Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Rahman MA, Bissa M, Silva de Castro I, Helmold Hait S, Stamos JD, Bhuyan F, Hunegnaw R, Sarkis S, Gutowska A, Doster MN, Moles R, Hoang T, Miller Jenkins LM, Appella E, Venzon DJ, Choo-Wosoba H, Cardozo T, Baum MM, Appella DH, Robert-Guroff M, Franchini G. Rahman MA, et al. Among authors: doster mn. Nat Microbiol. 2023 May;8(5):905-918. doi: 10.1038/s41564-023-01353-7. Epub 2023 Apr 6. Nat Microbiol. 2023. PMID: 37024617 Free PMC article.
Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure.
Vaccari M, Keele BF, Bosinger SE, Doster MN, Ma ZM, Pollara J, Hryniewicz A, Ferrari G, Guan Y, Forthal DN, Venzon D, Fenizia C, Morgan T, Montefiori D, Lifson JD, Miller CJ, Silvestri G, Rosati M, Felber BK, Pavlakis GN, Tartaglia J, Franchini G. Vaccari M, et al. Among authors: doster mn. J Virol. 2013 Mar;87(6):3538-48. doi: 10.1128/JVI.02863-12. Epub 2013 Jan 16. J Virol. 2013. PMID: 23325681 Free PMC article.
Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.
Vaccari M, Fenizia C, Ma ZM, Hryniewicz A, Boasso A, Doster MN, Miller CJ, Lindegardh N, Tarning J, Landay AL, Shearer GM, Franchini G. Vaccari M, et al. Among authors: doster mn. AIDS Res Hum Retroviruses. 2014 Apr;30(4):355-62. doi: 10.1089/AID.2013.0218. Epub 2013 Dec 24. AIDS Res Hum Retroviruses. 2014. PMID: 24251542 Free PMC article.
Antiretroviral therapy partly reverses the systemic and mucosal distribution of NK cell subsets that is altered by SIVmac₂₅₁ infection of macaques.
Liyanage NP, Gordon SN, Doster MN, Pegu P, Vaccari M, Shukur N, Schifanella L, Pise-Masison CA, Lipinska D, Grubczak K, Moniuszko M, Franchini G. Liyanage NP, et al. Among authors: doster mn. Virology. 2014 Feb;450-451:359-68. doi: 10.1016/j.virol.2013.12.003. Epub 2014 Jan 21. Virology. 2014. PMID: 24503100 Free PMC article.
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, Ackerman ME, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, Pegu P, Montefiori DC, Foulds K, Quinn DS, Donaldson M, Liang F, Loré K, Roederer M, Koup RA, McDermott A, Ma ZM, Miller CJ, Phan TB, Forthal DN, Blackburn M, Caccuri F, Bissa M, Ferrari G, Kalyanaraman V, Ferrari MG, Thompson D, Robert-Guroff M, Ratto-Kim S, Kim JH, Michael NL, Phogat S, Barnett SW, Tartaglia J, Venzon D, Stablein DM, Alter G, Sekaly RP, Franchini G. Vaccari M, et al. Among authors: doster mn. Nat Med. 2016 Jul;22(7):762-70. doi: 10.1038/nm.4105. Epub 2016 May 30. Nat Med. 2016. PMID: 27239761 Free PMC article.
28 results