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Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response.
Rahman MA, Bissa M, Scinto H, Howe SE, Sarkis S, Ma ZM, Gutowska A, Jiang X, Luo CC, Schifanella L, Moles R, Silva de Castro I, Basu S, N'guessan KF, Williams LD, Becerra-Flores M, Doster MN, Hoang T, Choo-Wosoba H, Woode E, Sui Y, Tomaras GD, Paquin-Proulx D, Rao M, Talton JD, Kong XP, Zolla-Pazner S, Cardozo T, Franchini G, Berzofsky JA. Rahman MA, et al. Among authors: berzofsky ja. Nat Commun. 2024 Oct 22;15(1):9102. doi: 10.1038/s41467-024-53359-2. Nat Commun. 2024. PMID: 39438480 Free PMC article.
Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response.
Sui Y, Lewis GK, Wang Y, Berckmueller K, Frey B, Dzutsev A, Vargas-Inchaustegui D, Mohanram V, Musich T, Shen X, DeVico A, Fouts T, Venzon D, Kirk J, Waters RC, Talton J, Klinman D, Clements J, Tomaras GD, Franchini G, Robert-Guroff M, Trinchieri G, Gallo RC, Berzofsky JA. Sui Y, et al. Among authors: berzofsky ja. J Clin Invest. 2019 Mar 1;129(3):1314-1328. doi: 10.1172/JCI122110. Epub 2019 Feb 18. J Clin Invest. 2019. PMID: 30776026 Free PMC article.
Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate.
Vaccari M, Fourati S, Brown DR, Silva de Castro I, Bissa M, Schifanella L, Doster MN, Foulds KE, Roederer M, Koup RA, Sui Y, Berzofsky JA, Sekaly RP, Franchini G. Vaccari M, et al. Among authors: berzofsky ja. Front Immunol. 2019 May 14;10:1072. doi: 10.3389/fimmu.2019.01072. eCollection 2019. Front Immunol. 2019. PMID: 31139193 Free PMC article.
Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques.
Sui Y, Zhu Q, Gagnon S, Dzutsev A, Terabe M, Vaccari M, Venzon D, Klinman D, Strober W, Kelsall B, Franchini G, Belyakov IM, Berzofsky JA. Sui Y, et al. Among authors: berzofsky ja. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9843-8. doi: 10.1073/pnas.0911932107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457926 Free PMC article.
TLR agonists and/or IL-15 adjuvanted mucosal SIV vaccine reduced gut CD4⁺ memory T cell loss in SIVmac251-challenged rhesus macaques.
Sui Y, Gagnon S, Dzutsev A, Zhu Q, Yu H, Hogg A, Wang Y, Xia Z, Belyakov IM, Venzon D, Klinman D, Strober W, Kelsall B, Franchini G, Berzofsky JA. Sui Y, et al. Among authors: berzofsky ja. Vaccine. 2011 Dec 9;30(1):59-68. doi: 10.1016/j.vaccine.2011.10.043. Epub 2011 Oct 29. Vaccine. 2011. PMID: 22041305 Free PMC article.
Nonhuman primate models for HIV/AIDS vaccine development.
Sui Y, Gordon S, Franchini G, Berzofsky JA. Sui Y, et al. Among authors: berzofsky ja. Curr Protoc Immunol. 2013 Oct 1;102:12.14.1-12.14.30. doi: 10.1002/0471142735.im1214s102. Curr Protoc Immunol. 2013. PMID: 24510515 Free PMC article. Review.
A Prime/Boost Vaccine Regimen Alters the Rectal Microbiome and Impacts Immune Responses and Viremia Control Post-Simian Immunodeficiency Virus Infection in Male and Female Rhesus Macaques.
Musich T, Thovarai V, Venzon DJ, Mohanram V, Tuero I, Miller-Novak LK, Helmold Hait S, Rahman MA, Hunegnaw R, Huiting E, Yuan W, O'hUigin C, Hoang T, Sui Y, LaBranche C, Montefiori D, Bear J, Rosati M, Bissa M, Berzofsky JA, Pavlakis GN, Felber BK, Franchini G, Robert-Guroff M. Musich T, et al. Among authors: berzofsky ja. J Virol. 2020 Nov 23;94(24):e01225-20. doi: 10.1128/JVI.01225-20. Print 2020 Nov 23. J Virol. 2020. PMID: 32967951 Free PMC article.
461 results