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Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Jain AK, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X. Zhou J, et al. Among authors: ren r. Cell Chem Biol. 2024 Dec 19;31(12):2112-2127.e6. doi: 10.1016/j.chembiol.2024.09.007. Epub 2024 Oct 21. Cell Chem Biol. 2024. PMID: 39437789 Free article.
Detecting and interpreting DNA methylation marks.
Ren R, Horton JR, Zhang X, Blumenthal RM, Cheng X. Ren R, et al. Curr Opin Struct Biol. 2018 Dec;53:88-99. doi: 10.1016/j.sbi.2018.06.004. Epub 2018 Jul 19. Curr Opin Struct Biol. 2018. PMID: 30031306 Free PMC article. Review.
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
Zhou J, Horton JR, Menna M, Fiorentino F, Ren R, Yu D, Hajian T, Vedadi M, Mazzoccanti G, Ciogli A, Weinhold E, Hüben M, Blumenthal RM, Zhang X, Mai A, Rotili D, Cheng X. Zhou J, et al. Among authors: ren r. J Med Chem. 2023 Jan 12;66(1):934-950. doi: 10.1021/acs.jmedchem.2c01789. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36581322 Free PMC article.
Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X. Zhou J, et al. Among authors: ren r. bioRxiv [Preprint]. 2024 Apr 3:2024.04.03.587980. doi: 10.1101/2024.04.03.587980. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Dec 19;31(12):2112-2127.e6. doi: 10.1016/j.chembiol.2024.09.007 PMID: 38617249 Free PMC article. Updated. Preprint.
1,617 results