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Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces apoptosis.
Gregory MD, Ofosu-Asante K, Lazarte JMS, Puente PE, Tawfeeq N, Belony N, Huang Y, Offringa IA, Lamango NS. Gregory MD, et al. Among authors: puente pe. PLoS One. 2024 Oct 22;19(10):e0312563. doi: 10.1371/journal.pone.0312563. eCollection 2024. PLoS One. 2024. PMID: 39436906 Free PMC article.
Lack of racial and ethnic diversity in lung cancer cell lines contributes to lung cancer health disparities.
Leon C, Manley E Jr, Neely AM, Castillo J, Ramos Correa M, Velarde DA, Yang M, Puente PE, Romero DI, Ren B, Chai W, Gladstone M, Lamango NS, Huang Y, Offringa IA. Leon C, et al. Among authors: puente pe. Front Oncol. 2023 Nov 1;13:1187585. doi: 10.3389/fonc.2023.1187585. eCollection 2023. Front Oncol. 2023. PMID: 38023251 Free PMC article. Review.