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The STAT3/SETDB2 axis dictates NF-κB-mediated inflammation in macrophages during wound repair.
Mangum KD, denDekker A, Li Q, Tsoi LC, Joshi AD, Melvin WJ, Wolf SJ, Moon JY, Audu CO, Shadiow J, Obi AT, Wasikowski R, Barrett EC, Bauer TM, Boyer K, Ahmed Z, Davis FM, Gudjonsson J, Gallagher KA. Mangum KD, et al. Among authors: wolf sj. JCI Insight. 2024 Oct 22;9(20):e179017. doi: 10.1172/jci.insight.179017. JCI Insight. 2024. PMID: 39435663 Free PMC article.
TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF.
denDekker AD, Davis FM, Joshi AD, Wolf SJ, Allen R, Lipinski J, Nguyen B, Kirma J, Nycz D, Bermick J, Moore BB, Gudjonsson JE, Kunkel SL, Gallagher KA. denDekker AD, et al. Among authors: wolf sj. JCI Insight. 2020 Mar 12;5(5):e132306. doi: 10.1172/jci.insight.132306. JCI Insight. 2020. PMID: 32069267 Free PMC article.
Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair.
Davis FM, denDekker A, Kimball A, Joshi AD, El Azzouny M, Wolf SJ, Obi AT, Lipinski J, Gudjonsson JE, Xing X, Plazyo O, Audu C, Melvin WJ, Singer K, Henke PK, Moore BB, Burant C, Kunkel SL, Gallagher KA. Davis FM, et al. Among authors: wolf sj. J Immunol. 2020 May 1;204(9):2503-2513. doi: 10.4049/jimmunol.1901263. Epub 2020 Mar 23. J Immunol. 2020. PMID: 32205424 Free PMC article.
Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair.
Davis FM, Tsoi LC, Wasikowski R, denDekker A, Joshi A, Wilke C, Deng H, Wolf S, Obi A, Huang S, Billi AC, Robinson S, Lipinski J, Melvin WJ, Audu CO, Weidinger S, Kunkel SL, Smith A, Gudjonsson JE, Moore BB, Gallagher KA. Davis FM, et al. JCI Insight. 2020 Sep 3;5(17):e138443. doi: 10.1172/jci.insight.138443. JCI Insight. 2020. PMID: 32879137 Free PMC article.
Macrophage-mediated inflammation in diabetic wound repair.
Wolf SJ, Melvin WJ, Gallagher K. Wolf SJ, et al. Semin Cell Dev Biol. 2021 Nov;119:111-118. doi: 10.1016/j.semcdb.2021.06.013. Epub 2021 Jun 26. Semin Cell Dev Biol. 2021. PMID: 34183242 Free PMC article. Review.
Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2.
Melvin WJ, Audu CO, Davis FM, Sharma SB, Joshi A, DenDekker A, Wolf S, Barrett E, Mangum K, Zhou X, Bame M, Ruan A, Obi A, Kunkel SL, Moore BB, Gallagher KA. Melvin WJ, et al. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2101071118. doi: 10.1073/pnas.2101071118. Proc Natl Acad Sci U S A. 2021. PMID: 34479991 Free PMC article.
IFN-κ is critical for normal wound repair and is decreased in diabetic wounds.
Wolf SJ, Audu CO, Joshi A, denDekker A, Melvin WJ, Davis FM, Xing X, Wasikowski R, Tsoi LC, Kunkel SL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM, Gallagher KA. Wolf SJ, et al. JCI Insight. 2022 May 9;7(9):e152765. doi: 10.1172/jci.insight.152765. JCI Insight. 2022. PMID: 35358091 Free PMC article.
Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.
Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi B, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Audu CO, et al. Among authors: wolf sj. Cell Mol Immunol. 2022 Nov;19(11):1251-1262. doi: 10.1038/s41423-022-00919-5. Epub 2022 Sep 20. Cell Mol Immunol. 2022. PMID: 36127466 Free PMC article.
93 results