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o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
Rahaman MH, Thygesen SJ, Maxwell MJ, Kim H, Mudai P, Nanson JD, Jia X, Vajjhala PR, Hedger A, Vetter I, Haselhorst T, Robertson AAB, Dymock B, Ve T, Mobli M, Stacey KJ, Kobe B. Rahaman MH, et al. Among authors: robertson aab. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2313055. doi: 10.1080/14756366.2024.2313055. Epub 2024 Feb 28. J Enzyme Inhib Med Chem. 2024. PMID: 38416868 Free PMC article.
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
Chitty JL, Blake KL, Blundell RD, Koh YQAE, Thompson M, Robertson AAB, Butler MS, Cooper MA, Kappler U, Williams SJ, Kobe B, Fraser JA. Chitty JL, et al. Among authors: robertson aab. J Biol Chem. 2017 Jul 14;292(28):11829-11839. doi: 10.1074/jbc.M117.787994. Epub 2017 May 30. J Biol Chem. 2017. PMID: 28559277 Free PMC article.
Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion.
Donovan C, Kim RY, Galvao I, Jarnicki AG, Brown AC, Jones-Freeman B, Gomez HM, Wadhwa R, Hortle E, Jayaraman R, Khan H, Pickles S, Sahu P, Chimankar V, Tu X, Ali MK, Mayall JR, Nguyen DH, Budden KF, Kumar V, Schroder K, Robertson AA, Cooper MA, Wark PA, Oliver BG, Horvat JC, Hansbro PM. Donovan C, et al. Immunol Cell Biol. 2022 Apr;100(4):235-249. doi: 10.1111/imcb.12537. Epub 2022 Mar 21. Immunol Cell Biol. 2022. PMID: 35175629 Free PMC article.
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma.
Pinkerton JW, Kim RY, Brown AC, Rae BE, Donovan C, Mayall JR, Carroll OR, Khadem Ali M, Scott HA, Berthon BS, Baines KJ, Starkey MR, Kermani NZ, Guo YK, Robertson AAB, O'Neill LAJ, Adcock IM, Cooper MA, Gibson PG, Wood LG, Hansbro PM, Horvat JC. Pinkerton JW, et al. Among authors: robertson aab. J Allergy Clin Immunol. 2022 Apr;149(4):1270-1280. doi: 10.1016/j.jaci.2021.10.003. Epub 2021 Oct 19. J Allergy Clin Immunol. 2022. PMID: 34678326
86 results