Zhang L - Search Results

1

Discovery of ZG-2305, an Orally Bioavailable Factor Inhibiting HIF Inhibitor for the Treatment of Obesity and Fatty Liver Disease.

Wu Y, Zhang Z, Cai H, Zhang W, Zhang L, Li Z, Yang L, Chen Y, Corner TP, Song Z, Yue J, Yang F, Li X, Schofield CJ, Zhang X. Wu Y, et al. Among authors: zhang l, zhang w, zhang z, zhang x. J Med Chem. 2024 Oct 21. doi: 10.1021/acs.jmedchem.4c01698. Online ahead of print. J Med Chem. 2024. PMID: 39432709

2

Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia.

Wu Y, Zhang L, Sun Z, Qiu X, Chen Y, Su K, Yang L, Du Z, Dong Y, Yang F, Li X, Zhang X. Wu Y, et al. Among authors: zhang l, zhang x. J Med Chem. 2023 Jul 13;66(13):8545-8563. doi: 10.1021/acs.jmedchem.3c00231. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37367818

3

A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-Flip Pocket for the Treatment of Obesity.

Wu Y, Chen Y, Corner TP, Nakashima Y, Salah E, Li Z, Zhang L, Yang L, Tumber A, Sun Z, Wen Y, Zhong A, Yang F, Li X, Zhang Z, Schofield CJ, Zhang X. Wu Y, et al. Among authors: zhang l, zhang z, zhang x. Angew Chem Int Ed Engl. 2024 Oct 1;63(40):e202410438. doi: 10.1002/anie.202410438. Epub 2024 Jul 31. Angew Chem Int Ed Engl. 2024. PMID: 38923188

4

Tetrahydropyridin-4-ylpicolinoylglycines as novel and orally active prolyl hydroxylase 2 (PHD2) inhibitors for the treatment of renal anemia.

Su K, Li Z, Zhang L, Fang S, Mao M, Sun Z, Zhang X. Su K, et al. Among authors: zhang l, zhang x. Eur J Med Chem. 2022 Aug 5;238:114479. doi: 10.1016/j.ejmech.2022.114479. Epub 2022 May 25. Eur J Med Chem. 2022. PMID: 35675755

5

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery.

Li Z, Wu Y, Zhen S, Su K, Zhang L, Yang F, McDonough MA, Schofield CJ, Zhang X. Li Z, et al. Among authors: zhang l, zhang x. Angew Chem Int Ed Engl. 2022 Nov 7;61(45):e202211510. doi: 10.1002/anie.202211510. Epub 2022 Oct 11. Angew Chem Int Ed Engl. 2022. PMID: 36112310 Free PMC article.

6

Corrigendum to "Tetrahydropyridin-4-ylpicolinoylglycines as novel and orally active prolyl hydroxylase 2 (PHD2) inhibitors for the treatment of renal anemia" [Eur. J. Med. Chem. 238 (2022) 114479].

Su K, Li Z, Zhang L, Fang S, Mao M, Sun Z, Zhang X. Su K, et al. Among authors: zhang l, zhang x. Eur J Med Chem. 2023 Nov 5;259:115692. doi: 10.1016/j.ejmech.2023.115692. Epub 2023 Aug 6. Eur J Med Chem. 2023. PMID: 37550158 No abstract available.

7

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery.

Li Z, Wu Y, Zhen S, Su K, Zhang L, Yang F, McDonough MA, Schofield CJ, Zhang X. Li Z, et al. Among authors: zhang l, zhang x. Angew Chem Weinheim Bergstr Ger. 2022 Nov 7;134(45):e202211510. doi: 10.1002/ange.202211510. Epub 2022 Oct 10. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505687 Free PMC article.

8

SUZ12-Increased NRF2 Alleviates Cardiac Ischemia/Reperfusion Injury by Regulating Apoptosis, Inflammation, and Ferroptosis.

Zhang G, Ma Z, Ma Z, Liu P, Zhang L, Lian Z, Guo C. Zhang G, et al. Among authors: zhang l. Cardiovasc Toxicol. 2024 Dec 27. doi: 10.1007/s12012-024-09950-6. Online ahead of print. Cardiovasc Toxicol. 2024. PMID: 39729180

9

Development and validation of a radiomics nomogram for preoperative prediction of BRAF^V600E mutation status in adult patients with craniopharyngioma.

Qiao N, Li C, Zheng F, Zhang L, Ma G, Jia Y, Cai K, Chen X, Lu P, Zhang Y, Gui S. Qiao N, et al. Among authors: zhang l. Neurosurg Rev. 2024 Dec 27;48(1):8. doi: 10.1007/s10143-024-03170-w. Neurosurg Rev. 2024. PMID: 39729136

10

Retraction Note: Monitoring of COS, SO₂, H₂S, and CS₂ gases by Al₂₄P₂₄ nanoclusters: a DFT inspection.

Wang A, Cui J, Zhang L, Liang L, Cao Y, Liu Q. Wang A, et al. Among authors: zhang l. J Mol Model. 2024 Dec 27;31(1):29. doi: 10.1007/s00894-024-06262-y. J Mol Model. 2024. PMID: 39729120 No abstract available.

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