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Long-term 3D cell culture models for hepatitis B virus studies.
Jones CE, Dangas G, Norris AC, Koenig M, Li DY, Shue TM, Athanasiadis A, Barbosa L, Zhou Y, Levenson KC, Zou C, de Jong YP, Michailidis E. Jones CE, et al. Among authors: de jong yp. Virology. 2024 Dec;600:110265. doi: 10.1016/j.virol.2024.110265. Epub 2024 Oct 18. Virology. 2024. PMID: 39427481
WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma.
Rialdi A, Duffy M, Scopton AP, Fonseca F, Zhao JN, Schwarz M, Molina-Sanchez P, Mzoughi S, Arceci E, Abril-Fornaguera J, Meadows A, Ruiz de Galarreta M, Torre D, Reyes K, Lim YT, Rosemann F, Khan ZM, Mohammed K, Wang X, Yu X, Lakshmanan M, Rajarethinam R, Tan SY, Jin J, Villanueva A, Michailidis E, De Jong YP, Rice CM, Marazzi I, Hasson D, Llovet JM, Sobota RM, Lujambio A, Guccione E, Dar AC. Rialdi A, et al. Among authors: de jong yp. Nat Cancer. 2023 Aug;4(8):1157-1175. doi: 10.1038/s43018-023-00609-9. Epub 2023 Aug 3. Nat Cancer. 2023. PMID: 37537299 Free PMC article.
Mice Engrafted with Human Liver Cells.
de Jong YP. de Jong YP. Semin Liver Dis. 2024 Nov;44(4):405-415. doi: 10.1055/s-0044-1790601. Epub 2024 Sep 12. Semin Liver Dis. 2024. PMID: 39265638 Free PMC article. Review.
AAV vectors tested in perfused human livers.
Herzog RW, de Jong YP. Herzog RW, et al. Among authors: de jong yp. Nat Biotechnol. 2025 Jan 29. doi: 10.1038/s41587-024-02539-y. Online ahead of print. Nat Biotechnol. 2025. PMID: 39881028 No abstract available.
Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1.
Shirani M, Levin S, Shebl B, Requena D, Finkelstein TM, Johnson DS, Ng D, Lalazar G, Heissel S, Hojrup P, Molina H, de Jong YP, Rice CM, Singhi AD, Torbenson MS, Coffino P, Lyons B, Simon SM. Shirani M, et al. Among authors: de jong yp. Cancer Res. 2024 Aug 15;84(16):2626-2644. doi: 10.1158/0008-5472.CAN-23-4110. Cancer Res. 2024. PMID: 38888469 Free PMC article.
Innate Immune Sensing of Adeno-Associated Virus Vectors.
Cao D, Byrne BJ, de Jong YP, Terhorst C, Duan D, Herzog RW, Kumar SRP. Cao D, et al. Among authors: de jong yp. Hum Gene Ther. 2024 Jul;35(13-14):451-463. doi: 10.1089/hum.2024.040. Epub 2024 Jul 5. Hum Gene Ther. 2024. PMID: 38887999 Review.
Optimizing liver health before and after gene therapy for hemophilia A.
Ragni MV, Mead H, de Jong YP, Kaczmarek R, Leavitt AD, Long B, Nugent DJ, Sabatino DE, Fong S, von Drygalski A, Walsh CE, Luxon BA. Ragni MV, et al. Among authors: de jong yp. Blood Adv. 2024 Oct 8;8(19):5203-5212. doi: 10.1182/bloodadvances.2024013059. Blood Adv. 2024. PMID: 38843379 Free PMC article. Review.
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