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An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
Connor-Robson N, Booth H, Martin JG, Gao B, Li K, Doig N, Vowles J, Browne C, Klinger L, Juhasz P, Klein C, Cowley SA, Bolam P, Hirst W, Wade-Martins R. Connor-Robson N, et al. Among authors: klein c. Neurobiol Dis. 2019 Jul;127:512-526. doi: 10.1016/j.nbd.2019.04.005. Epub 2019 Apr 5. Neurobiol Dis. 2019. PMID: 30954703 Free PMC article.
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1.
Chemla A, Arena G, Saraiva C, Berenguer-Escuder C, Grossmann D, Grünewald A, Klein C, Seibler P, Schwamborn JC, Krüger R. Chemla A, et al. Among authors: klein c. Stem Cell Res. 2023 Jun;69:103085. doi: 10.1016/j.scr.2023.103085. Epub 2023 Mar 25. Stem Cell Res. 2023. PMID: 37003181 Free PMC article.
Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation.
Gomez Ramos B, Ohnmacht J, de Lange N, Valceschini E, Ginolhac A, Catillon M, Ferrante D, Rakovic A, Halder R, Massart F, Arena G, Antony P, Bolognin S, Klein C, Krause R, Schulz MH, Sauter T, Krüger R, Sinkkonen L. Gomez Ramos B, et al. Among authors: klein c. EMBO Rep. 2024 Jan;25(1):254-285. doi: 10.1038/s44319-023-00024-2. Epub 2023 Dec 19. EMBO Rep. 2024. PMID: 38177910 Free PMC article.
Global Perspectives on Returning Genetic Research Results in Parkinson Disease.
Tan AH, Saffie-Awad P, Schumacher Schuh AF, Lim SY, Madoev H, Ahmad-Annuar A, Solle J, Wegel CE, Doquenia ML, Dey S, Perinan MT, Makarious MB, Fiske B, Morris HR, Noyce AJ, Alcalay RN, Kumar KR, Klein C; Global Parkinson's Genetic Program (GP2). Tan AH, et al. Among authors: klein c. Neurol Genet. 2024 Dec 5;10(6):e200213. doi: 10.1212/NXG.0000000000200213. eCollection 2024 Dec. Neurol Genet. 2024. PMID: 39807215 Free PMC article.
Distinguishing Chronic Inflammatory Demyelinating Polyneuropathy From Mimic Disorders: The Role of Statistical Modeling.
Swart G, Skolka MP, Shelly S, Lewis RA, Allen JA, Dubey D, Niu Z, Spies J, Laughlin RS, Thakolwiboon S, Santilli AR, Rashed H, Mirman I, Swart A, Berini SE, Shouman K, Pinto MV, Mauermann ML, Mills JR, Dyck PJB, Harmsen WS, Mandrekar J, Klein CJ. Swart G, et al. Among authors: klein cj. J Peripher Nerv Syst. 2025 Mar;30(1):e12682. doi: 10.1111/jns.12682. J Peripher Nerv Syst. 2025. PMID: 39801067
4,054 results