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An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals.
Offersgaard A, Duarte Hernandez CR, Zhou Y, Duan Z, Gammeltoft KA, Hartmann KT, Fahnøe U, Marichal-Gallardo P, Alzua GP, Underwood AP, Sølund C, Weis N, Bonde JH, Christensen JP, Pedersen GK, Jensen HE, Holmbeck K, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: gottwein jm. Sci Rep. 2024 Jul 24;14(1):17039. doi: 10.1038/s41598-024-67570-0. Sci Rep. 2024. PMID: 39048693 Free PMC article.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: gottwein j. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. PMID: 38659941 Free PMC article. Preprint.
JFH1-based Core-NS2 genotype variants of HCV with genetic stability in vivo and in vitro: Important tools in the evaluation of virus neutralization.
Collignon L, Holmbeck K, Just A, Verhoye L, Velázquez-Moctezuma R, Fahnøe U, Carlsen THR, Law M, Prentoe J, Scheel TKH, Gottwein JM, Meuleman P, Bukh J. Collignon L, et al. Among authors: gottwein jm. Hepatology. 2024 Nov 1;80(5):1227-1238. doi: 10.1097/HEP.0000000000000897. Epub 2024 Apr 23. Hepatology. 2024. PMID: 38652584
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
Sherwood AV, Rivera-Rangel LR, Ryberg LA, Larsen HS, Anker KM, Costa R, Vågbø CB, Jakljevič E, Pham LV, Fernandez-Antunez C, Indrisiunaite G, Podolska-Charlery A, Grothen JER, Langvad NW, Fossat N, Offersgaard A, Al-Chaer A, Nielsen L, Kuśnierczyk A, Sølund C, Weis N, Gottwein JM, Holmbeck K, Bottaro S, Ramirez S, Bukh J, Scheel TKH, Vinther J. Sherwood AV, et al. Among authors: gottwein jm. Nature. 2023 Jul;619(7971):811-818. doi: 10.1038/s41586-023-06301-3. Epub 2023 Jul 5. Nature. 2023. PMID: 37407817 Free PMC article.
Toward a vaccine against hepatitis C virus.
Offersgaard A, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: gottwein jm. Science. 2023 Apr 7;380(6640):37-38. doi: 10.1126/science.adf2226. Epub 2023 Apr 6. Science. 2023. PMID: 37023205
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals.
Offersgaard A, Duarte Hernandez CR, Feng S, Marichal-Gallardo P, Holmbeck K, Pihl AF, Fernandez-Antunez C, Alzua GP, Hartmann KT, Pham LV, Zhou Y, Gammeltoft KA, Fahnøe U, Schneider UV, Pedersen GK, Jensen HE, Christensen JP, Ramirez S, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: gottwein jm. iScience. 2023 Feb 17;26(2):105949. doi: 10.1016/j.isci.2023.105949. Epub 2023 Jan 10. iScience. 2023. PMID: 36644321 Free PMC article.
73 results