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Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1.
Panfili E, Rezzi SJ, Adamo A, Mazzoletti D, Massarotti A, Miggiano R, Fallarini S, Ambrosino S, Coletti A, Molinaro P, Milella M, Paiella S, Macchiarulo A, Ugel S, Pirali T, Pallotta MT. Panfili E, et al. Among authors: ugel s. ACS Pharmacol Transl Sci. 2024 Sep 12;7(10):3056-3070. doi: 10.1021/acsptsci.4c00265. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39421661
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.
Mondanelli G, Bianchi R, Pallotta MT, Orabona C, Albini E, Iacono A, Belladonna ML, Vacca C, Fallarino F, Macchiarulo A, Ugel S, Bronte V, Gevi F, Zolla L, Verhaar A, Peppelenbosch M, Mazza EMC, Bicciato S, Laouar Y, Santambrogio L, Puccetti P, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: ugel s. Immunity. 2017 Feb 21;46(2):233-244. doi: 10.1016/j.immuni.2017.01.005. Epub 2017 Feb 14. Immunity. 2017. PMID: 28214225 Free PMC article.
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity.
Serafini M, Torre E, Aprile S, Grosso ED, Gesù A, Griglio A, Colombo G, Travelli C, Paiella S, Adamo A, Orecchini E, Coletti A, Pallotta MT, Ugel S, Massarotti A, Pirali T, Fallarini S. Serafini M, et al. Among authors: ugel s. J Med Chem. 2020 Mar 26;63(6):3047-3065. doi: 10.1021/acs.jmedchem.9b01809. Epub 2020 Mar 17. J Med Chem. 2020. PMID: 32150677
Moonlighting Proteins Are Important Players in Cancer Immunology.
Adamo A, Frusteri C, Pallotta MT, Pirali T, Sartoris S, Ugel S. Adamo A, et al. Among authors: ugel s. Front Immunol. 2021 Jan 18;11:613069. doi: 10.3389/fimmu.2020.613069. eCollection 2020. Front Immunol. 2021. PMID: 33584695 Free PMC article. Review.
HER2 Aberrations in NSCLC: So Close Yet So Far.
Sartori G, Belluomini L, Trovato R, Minari R, Caliò A, Ugel S, Milella M, Pilotto S. Sartori G, et al. Among authors: ugel s. JCO Precis Oncol. 2020 Nov;4:1049-1051. doi: 10.1200/PO.20.00195. JCO Precis Oncol. 2020. PMID: 35050770 No abstract available.
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy.
Canè S, Barouni RM, Fabbi M, Cuozzo J, Fracasso G, Adamo A, Ugel S, Trovato R, De Sanctis F, Giacca M, Lawlor R, Scarpa A, Rusev B, Lionetto G, Paiella S, Salvia R, Bassi C, Mandruzzato S, Ferrini S, Bronte V. Canè S, et al. Among authors: ugel s. Sci Transl Med. 2023 Mar 15;15(687):eabq6221. doi: 10.1126/scitranslmed.abq6221. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921034
Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients.
Adamo A, Frusteri C, Pilotto S, Caligola S, Belluomini L, Poffe O, Giacobazzi L, Dusi S, Musiu C, Hu Y, Wang T, Rizzini D, Vella A, Canè S, Sartori G, Insolda J, Sposito M, Incani UC, Carbone C, Piro G, Pettinella F, Qi F, Wang D, Sartoris S, De Sanctis F, Scapini P, Dusi S, Cassatella MA, Bria E, Milella M, Bronte V, Ugel S. Adamo A, et al. Among authors: ugel s. Oncoimmunology. 2023 Sep 14;12(1):2253644. doi: 10.1080/2162402X.2023.2253644. eCollection 2023. Oncoimmunology. 2023. PMID: 37720688 Free PMC article.
89 results